Large-cap stocks are known for their staying power and ability to weather market storms better than smaller competitors. However, their sheer size makes it more challenging to maintain high growth rates as they’ve already captured significant portions of their markets.
This dynamic can trouble even the most skilled investors, but luckily for you, we started StockStory to help you navigate these trade-offs and uncover exceptional companies that break the mold. Keeping that in mind, here is one large-cap stock that still has big upside potential and two that could be stalling.
Two Large-Cap Stocks to Sell:
Agilent (A)
Market Cap: $42.37 billion
Originally spun off from Hewlett-Packard in 1999 as its measurement and analytical division, Agilent Technologies (NYSE: A) provides analytical instruments, software, services, and consumables for laboratory workflows in life sciences, diagnostics, and applied chemical markets.
Why Are We Wary of A?
- Muted 3.7% annual revenue growth over the last five years shows its demand lagged behind its healthcare peers
- Absence of organic revenue growth over the past two years suggests it may have to lean into acquisitions to drive its expansion
- Diminishing returns on capital suggest its earlier profit pools are drying up
Agilent is trading at $149.85 per share, or 22.3x forward P/E. Dive into our free research report to see why there are better opportunities than A.
M&T Bank (MTB)
Market Cap: $33.99 billion
Tracing its roots back to 1856 when it was founded as Manufacturers and Traders Bank in Buffalo, New York, M&T Bank (NYSE: MTB) is a regional bank holding company that provides retail and commercial banking, trust, wealth management, and investment services to consumers and businesses.
Why Are We Hesitant About MTB?
- Annual revenue growth of 3.9% over the last two years was below our standards for the banking sector
- Estimated net interest income growth of 3.1% for the next 12 months implies demand will slow from its five-year trend
- Anticipated tangible book value per share growth of 8% for the next year implies profitability will be modest
M&T Bank’s stock price of $235.32 implies a valuation ratio of 1.3x forward P/B. Read our free research report to see why you should think twice about including MTB in your portfolio.
One Large-Cap Stock to Buy:
Ameriprise Financial (AMP)
Market Cap: $49.41 billion
Founded in 1894 and spun off from American Express in 2005, Ameriprise Financial (NYSE: AMP) provides financial planning, wealth management, asset management, and insurance products to help individuals and institutions achieve their financial goals.
What Makes AMP Stand Out?
- Share buybacks propelled its annual earnings per share growth to 20.8%, which outperformed its revenue gains over the last five years
- Annual tangible book value per share growth of 19.1% over the past two years was outstanding, reflecting strong capital accumulation this cycle
- Market-beating return on equity illustrates that management has a knack for investing in profitable ventures
At $559.13 per share, Ameriprise Financial trades at 11.4x forward P/E. Is now the time to initiate a position? Find out in our full research report, it’s free.
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Stocks that made our list in 2020 include now familiar names such as Nvidia (+1,460% between June 2020 and June 2025) as well as under-the-radar businesses like the once-small-cap company Comfort Systems (+1,154% between June 2020 and June 2025). Find your next big winner with StockStory today.
