TOKYO, JAPAN - July 17, 2025 - 12:00 AM Mountain Time -Shugo Tohyama, professor at Fujita Medical Innovation Center (FMiC), Fujita Health University in Tokyo, project leader at Kanagawa Institute of Industrial and Science Technology (KISTEC), and team leader at Keio University Regenerative Medicine Research Center, and Taijun Moriwaki, assistant professor at FMiC, Fujita Health University in Tokyo, KISTEC, along with others recently published a research paper in the Cell Press journal ‘’STAR Protocols’’, jointly describing a protocol for production of homogeneous iPSC spheroids and microtissues using the suction technique with 3D cell culture substrata CERAHIVE® developed by CoorsTek (Japan headquarters: Shinagawa-ku, Tokyo, Japan).
This research paper details the development of CERAHIVE® culture technology, which allows for producing homogeneous uniform induced pluripotent stem cell (iPSC) spheroids and microtissues by aspirating media from cell suspensions and rapidly aggregating cells.
3D cell cultures will play an increasingly important role in disease modeling, drug efficacy evaluation, and toxicity testing. Researchers have discovered numerous advantages from innovative 3D tissue engineering methods, including increased efficiency, improved functionality, homogeneity, and spheroidization. The scalability of these methods also paves the way for mass production of these 3D structures, making them a valuable resource in regenerative medicine and drug discovery.
"The CERAHIVE® platform is a nice example of how we are supporting the rapid advancements in bio-medical research," said Randel Mercer, chief technology officer at CoorsTek. "We congratulate the dedicated teams at Fujita Health University, KISTEC and Keio University for utilizing our products to publish this research and look forward to future developments accelerating regenerative medicine.”
Please visit the following URL for the newly published research paper.
https://star-protocols.cell.com/protocols/4274
About CoorsTek
Founded in 1910, CoorsTek is a leading global manufacturer of advanced materials. By leveraging expertise in engineering and materials science, CoorsTek provides solutions to complex technical challenges in the semiconductor, medical, aerospace, and other industries. With over 400 proprietary formulations, vertically integrated systems, and unparalleled process capabilities, CoorsTek partners with its customers to make the world measurably better.
Media Contact:
Nobuko Matsumoto
Communications, CoorsTek (Japan)
nobuko_matsumoto@coorstek.com
+81-3-5437-6182
