FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * MEISTER PAUL M   2. Issuer Name and Ticker or Trading Symbol THERMO FISHER SCIENTIFIC INC. [TMO] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 81 WYMAN STREET, P.O. BOX 9046 3. Date of Earliest Transaction (Month/Day/Year) 11/09/2006 (Street) WALTHAM, MA 024549046 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 11/09/2006   A   350,000 A (1) 350,000 D   Common Stock 11/09/2006   A   150,000 A (2) 500,000 D   Common Stock 11/09/2006   A   48,460 A (3) 548,460 D   Common Stock 11/09/2006   F   72,339 D $ 43.37 476,121 D   Common Stock 11/09/2006   A   984,212 A (4) 984,212 I By Trusts (5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Stock Option (Right to Buy)

$ 4.75

11/09/2006

A

864,604

11/09/2006

01/21/2008

Common Stock

864,604

(6)

864,604

D

Stock Option (Right to Buy)

$ 19.62

11/09/2006

A

600,000

11/09/2006

09/26/2008

Common Stock

600,000

(7)

600,000

D

Stock Option (Right to Buy)

$ 12

11/09/2006

A

500,000

11/09/2006

05/03/2011

Common Stock

500,000

(8)

500,000

D

Stock Option (Right to Buy)

$ 15

11/09/2006

A

200,000

11/09/2006

05/03/2011

Common Stock

200,000

(9)

200,000

D

Stock Option (Right to Buy)

$ 14.2

11/09/2006

A

600,000

11/09/2006

01/27/2013

Common Stock

600,000

(10)

600,000

D

Stock Option (Right to Buy)

$ 43.37

11/09/2006

A

15,600

(11)

11/09/2013

Common Stock

15,600

$ 0

15,600

D

Stock Option (Right to Buy)

$ 30.68

11/09/2006

A

119,200

11/09/2006

03/07/2015

Common Stock

119,200

(12)

119,200

D

Stock Option (Right to Buy)

$ 32.3

11/09/2006

A

172,080

11/09/2006

07/25/2015

Common Stock

172,080

(13)

172,080

D

Stock Option (Right to Buy)

$ 30.68

11/09/2006

A

178,800

11/09/2006

03/07/2015

Common Stock

178,800

(14)

178,800

I

By Family Trust (15)

Stock Option (Right to Buy)

$ 32.3

11/09/2006

A

114,720

11/09/2006

07/25/2015

Common Stock

114,720

(16)

114,720

I

By Family Trust (15)

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
MEISTER PAUL M 81 WYMAN STREET P.O. BOX 9046 WALTHAM, MA 024549046	X

Signatures

By: Barbara J. Lucas, Attorney-in-Fact for Paul M. Meister		11/14/2006
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Received in exchange for 175,000 shares of Fisher Scientific International Inc. common stock in connection with the merger of Thermo Fisher Scientific Inc. (formerly known as Thermo Electron Corporation), Trumpet Merger Corporation and Fisher Scientific International Inc. ("FSH") (the "Merger"). On the effective date of the Merger, the closing price of FSH's common stock was $86.58 per share, and the closing price of TMO's common stock was $43.37 per share.
(2)	Received in exchange for 75,000 Restricted Stock Units accrued under FSH's 2005 Equity and Incentive Plan. The Restricted Stock Units were settled pursuant to the Merger for 2.0 shares of TMO common stock on the effective date of the Merger.
(3)	Received in exchange for 24,230 Restricted Stock Units accrued under FSH's 2005 Equity and Incentive Plan. The Restricted Stock Units were settled pursuant to the Merger for 2.0 shares of TMO common stock on the effective date of the Merger.
(4)	Received in exchange for 492,106 shares of FSH common stock in connection with the Merger. On the effective date of the Merger, the closing price of FSH's common stock was $86.58 per share, and the closing price of TMO's common stock was $43.37 per share.
(5)	The shares are held in a number of trusts for the benefit of the reporting person.
(6)	Received in the Merger in exchange for a stock option to acquire 432,302 shares of FSH common stock for $9.50 per share.
(7)	Received in the Merger in exchange for a stock option to acquire 300,000 shares of FSH common stock for $39.24 per share.
(8)	Received in the Merger in exchange for a stock option to acquire 250,000 shares of FSH common stock for $24.00 per share.
(9)	Received in the Merger in exchange for a stock option to acquire 100,000 shares of FSH common stock for $30.00 per share.
(10)	Received in the Merger in exchange for a stock option to acquire 300,000 shares of FSH common stock for $28.40 per share.
(11)	The option vests in three equal annual installments beginning on November 9, 2007.
(12)	Received in the Merger in exchange for a stock option to acquire 59,600 shares of FSH common stock for $61.35 per share.
(13)	Received in the Merger in exchange for a stock option to acquire 86,040 shares of FSH common stock for $64.60 per share.
(14)	Received in the Merger in exchange for a stock option to acquire 89,400 shares of FSH common stock for $61.35 per share.
(15)	These options are held by a family trust for the benefit of the reporting person.
(16)	Received in the Merger in exchange for a stock option to acquire 57,360 shares of FSH common stock for $64.60 per share.

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