SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934

                        Date of Report (Date of earliest
                          event reported) September 24,
                            2003 (September 23, 2003)

                           HEMISPHERX BIOPHARMA, INC.
             (Exact name of registrant as specified in its charter)



                           Delaware 0-27072 52-0845822
               (state or other juris- (Commission (I.R.S. Employer
           diction of incorporation) File Number) (Identification No.)


              1617 JFK Boulevard, Philadelphia, Pennsylvania 19103
               (Address of principal executive offices) (Zip Code)


       Registrant's telephone number, including area code: (215) 988-0080

          ------------------------------------------------------------
          (Former name or former address, if changed since last report)







ITEM 5.  OTHER EVENTS AND REGULATION FD DISCLOSURE.



         On September 23, 2003 Hemispherx Biopharma,  Inc. asked for service of,
and  moved  for  expedited  proceedings  on, a  Complaint  filed in the court of
chancery  of the  state  of  Delaware  in and  for  New  Castle  county  against
Interferon Sciences, Inc.

     The Complaint  seeks specific  performance,  and declaratory and injunctive
relief related to two agreements  entered into in March 2003 between  Hemispherx
Biopharma,  Inc, and Interferon  Sciences,  Inc.  Pursuant to these  agreements,
Hemispherx Biopharma,  Inc. is to acquire certain assets of Interferon Sciences,
Inc.




SIGNATURES


         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                          HEMISPHERX BIOPHARMA, INC.


September 23, 2003                     By: /s/ Willaim A. Carter
                                          ---------------------------------
                                          William A. Carter, M.D., President