FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * Sims Randall   2. Issuer Name and Ticker or Trading Symbol HOME BANCSHARES INC [HOMB] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) HOMB & Centennial Bank CEO (Last) (First) (Middle) P.O. BOX 966 3. Date of Earliest Transaction (Month/Day/Year) 11/04/2010 (Street) CONWAY, AR 72033 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 11/04/2010   S   19,034 D $ 21.8123 61,126 D   Common Stock 11/05/2010   S   4,697 D $ 22 56,429 D   Common Stock               2.0713 I By wife as custodian for Daniel Sims Common Stock               28,829 I By IRA Common Stock - Restricted               3,300 (2) D   Common Stock               5,409.706 (3) I By 401(k)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Stock Option

$ 6.17

(1)

(1)

Common Stock

29,159

29,159

D

Performance Stock Option

$ 11.09

01/01/2010

03/13/2016

Common Stock

35,582

35,582

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Sims Randall P.O. BOX 966 CONWAY, AR 72033	X		HOMB & Centennial Bank CEO

Signatures

/s/ Randall Sims by Rachel Starkey		11/05/2010
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The option is exercisable in five equal annual installments. The option expires 10 years from the exercisable date, therefore the first installment became exercisable on December 31, 1999 and expires on December 31, 2009.
(2)	Restricted Stock granted on January 22, 2010 will vest in 50% installments over two years each January 22nd. The 2009 participation by the Company in the United States Department of the Treasury's Trouble Asset Relief Program includes additional contingencies related to this restricted stock.
(3)	Includes 13.249 shares acquired through the Home BancShares, Inc. 401(k) Plan since the last filing.

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