SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549
                            -------------------------

                                    FORM 8-K

                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934

               Date of Earliest Event Reported: April 25, 2001



                       GreatBio Technologies, Inc.
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          (Exact name of registrant as specified in its charter)



         Nevada                         0-26057               82-0507874
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(State or other jurisdiction of  (Commission File Number)  (IRS Employer
 incorporation or organization)                          Identification No.)




       150 Lucius Gordon Drive,
          West Henrietta, NY                                       14586
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(Address of principal executive offices)                        (Zip Code)



       Registrant's telephone number, including area code (716) 214-2441
















ITEM 4.         CHANGE IN REGISTRANT'S CERTIFIYING ACCOUNTANTS

       (a)      Previous independent accountants

                On April 25, 2001, GreatBio Technologies, Inc. dismissed
                Arthur Andersen LLP as its independent accountants. The
                Registrant's Board of Directors approved the decision to
                change independent accountants. Arthur Andersen LLP issued no
                reports on the financial statements.  Arthur Andersen LLP was
                engaged from January 15, 2001 through April 24, 2001 and during
                such period there have been no disagreements with Arthur
                Andersen LLP on any matter of accounting principles or
                practices, financial statement disclosure, auditing scope or
                procedure, which disagreements if not resolved to the
                satisfaction of Arthur Andersen LLP would have caused them to
                make reference thereto in their report to be issued on the
                financial statements.  During the period in which Arthur
                Andersen LLP was engaged there have been no reportable events
                as defined in Regulation S-K Item 304(a)(1)(v). The
                Registrant has requested that Arthur Andersen LLP furnish
                it with a letter addressed to the SEC stating whether or not
                it agrees with the above statements. A copy of such letter,
                dated May 4, 2001, is filed as Exhibit 16 to this Form 8-K.

     (b)        New independent accountants

                The Registrant engaged Goldstein Golub Kessler LLP as its new
                independent accountants as of April 25, 2001. During the
                two most recent fiscal years and through April 25, 2001,
                the Registrant has not consulted with Goldstein Golub Kessler
                LLP regarding either (i) the application of accounting
                principles to a specified transaction, either completed or
                proposed; or the type of audit opinion that might be rendered
                on the Registrant's financial statements, and neither a
                written report nor oral advice was provided to the Registrant
                that was an important factor considered by the Registrant in
                reaching a decision as to the accounting, auditing or
                financial reporting issue; or (ii) any matter that was
                either the subject of a disagreement, as that term is defined
                in Item 304(a)(1)(iv) of Regulation S-K and the related
                instructions to Item 304 of Regulation S-K, or a reportable
                event, as that term is defined in Item 304(a)(1)(v) of
                Regulation S-K.














ITEM 7.         FINANCIAL STATEMENTS AND EXHIBITS

       (c)      Exhibits.
                                                                         Page

                (16)  Letter regarding change in certifying accountant.    3



                                 SIGNATURE

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned, thereunto duly authorized.

         Dated: May 3, 2001


                                               GreatBio Technologies, Inc.


                                               By: /s/ Michael L. Weiner
                                                  ----------------------------
                                               Name:    Michael L. Weiner
                                               Title:   President