SECURITIES AND EXCHANGE COMMISSION
                     Washington, D.C.  20549

                          SCHEDULE 13G/A
            Under the Securities Exchange Act of 1934


                     BioCryst Pharmaceuticals, Inc.
                        (Name of Issuer)

                 Common Stock ($0.01 par value)
                 (Title of Class of Securities)

                           09058V103
                         (CUSIP Number)

                       DECEMBER 31, 2011 YEAR END
      (Date of Event Which Requires Filing of this Statement)

     Check the appropriate box to designate the rule pursuant to
which this Schedule is filed:

        [ ] Rule 13d-1(b)
        [X] Rule 13d-1(c)
        [ ] Rule 13d-1(d)

     The remainder of this cover page shall be filled out for a
reporting person's initial filing on this form with respect to the
subject class of securities, and for any subsequent amendment containing
information which would alter the disclosures provided in a prior cover page.

     The information required on the remainder of this cover page
shall not be deemed to be "filed" for the purpose of Section 18
of the Securities Exchange Act of 1934 ("Act") or otherwise
subject to the liabilities of that section of the Act but shall
be subject to all other provisions of the Act (however, see the Notes).




CUSIP No.   09058V103
_________________________________________________________________

1    NAME OF REPORTING PERSON
     S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

          Joseph L. Harrosh
_________________________________________________________________

 2   CHECK THE APPROPRIATE BOX                         (a) [ ]
     IF A MEMBER OF A GROUP (See Instructions)         (b) [ ]
_________________________________________________________________

3    SEC USE ONLY
_________________________________________________________________

4    CITIZENSHIP OR PLACE OF ORGANIZATION         United States
_________________________________________________________________
                                   |
                                   |  (7) SOLE VOTING POWER
                                   |     Less than 5% SEE ITEM 5
                                   |_____________________________
                                   |
                                   |  (8)    SHARED VOTING POWER
                                   |         -0-
NUMBER OF SHARES BENEFICIALLY      |_____________________________
OWNED BY EACH REPORTING            |
PERSON WITH                        |  (9) SOLE DISPOSITIVE POWER
                                   |      Less than 5% SEE ITEM 5
                                   |_____________________________
                                   |
                                   | (10)    SHARED DISPOSITIVE
                                   |         POWER
                                   |         -0-
___________________________________|_____________________________

11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:
     Less than 5% SEE ITEM 5
_________________________________________________________________

12   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
     CERTAIN SHARES (See Instructions)                      [ ]
_________________________________________________________________

13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) :
      Less than 5% SEE ITEM 5
_________________________________________________________________

14   TYPE OF REPORTING PERSON                               IN
_________________________________________________________________
Item 1.
          (a)  Name of Issuer:
               BIOCRYST PHARMACEUTICALS, INC.
          (b)  Address of Issuer's Principal Executive Offices:
               4505 EMPEROR BLVD SUITE 200
               DURHAM, NORTH CAROLINA 27703
               PHONE - (919) 859-1302
Item 2.
          (a)  Name of Person Filing:
               Joseph L. Harrosh
          (b)  Address of Principal Business Office:
               P.O. BOX 6009
               FREMONT, CA 94538
               (925)523-3323
          (c)  Citizenship:
               United States
          (d)  Title of Class of Securities:
               Common Stock ($0.01 par value)
          (e)  CUSIP Number:
               09058v103
Item 3.   If this statement is filed pursuant to Sections 240.13d-1(b)
or 240.13d-2(b) or (c), check whether the person filing is a:

          (a) [ ]  Broker or dealer registered under Section 15 of the
          Act (15 U.S.C. 78o).
          (b) [ ]  Bank as defined in Section 3(a)(6) of the Act
          (15 U.S.C. 78c).
          (c) [ ]  Insurance company as defined in Section 3(a)(19) of
          the Act (15 U.S.C. 78c).
          (d) [ ]  Investment company registered under Section 8 of the
          Investment Company Act of 1940 (15 U.S.C. 80a-8).
          (e) [ ]  An investment adviser in accordance with Section
          240.13d-1(b)(1)(ii)(E);
          (f) [ ]  An employee benefit plan or endowment fund in accordance
          with Section 240.13d-1(b)(1)(ii)(F);
          (g) [ ]  A parent holding company or control person in accordance with
          Section 240.13d-1(b)(1)(ii)(G);
          (h) [ ]  A savings associations as defined in Section 3(b) of the
          Federal Deposit Insurance Act (12 U.S.C. 1813);
          (i) [ ]  A church plan that is excluded from the definition of an
          investment company under Section 3(c)(14) of the Investment Company
          Act of 1940 (15 U.S.C. 80a-3);
          (j) [ ]  Group, in accordance with Section 240.13d-1(b)(1)(ii)(J).

Item 4.   Ownership

          Provide the following information regarding the aggregate
number and percentage of the class of securities of the issuer identified
in Item 1.
          (a)  Amount beneficially owned:       Less than 5% SEE ITEM 5
          (b)  Percent of class:                     Less than 5% SEE ITEM 5
          (c)  Number of Shares as to which the person has:
               (i)    Sole power to vote or to direct to vote:
                      Less than 5% SEE ITEM 5
               (ii)   Share power to vote or to direct to vote:
                      0   Shares
               (iii)  Sole power to dispose or to direct the disposition of:
                      Less than 5% SEE ITEM 5
               (iv)   Shared power to dispose or to direct the disposition of:
                      0   Shares

Item 5.   Ownership of Five Percent or Less of a Class

          If this statement is being filed to report the fact that as of
the date hereof the reporting person has ceased to be the beneficial
owner of more than five percent of the class of securities, check the
following [x].

Item 6.   Ownership of More than Five Percent on Behalf of Another Person

          If any other person is known to have the right to receive or
the power to direct the receipt of dividends from, or the proceeds from
the sale of, such securities, a statement to that effect should be included
in response to this item and, if such interest relates to more than five
percent of the class, such person should be identified.  A listing of the
shareholders of an investment company registered under the Investment
Company Act of 1940 or the beneficiaries of empolyee benefit plan pension
fund endowment fund is not required.

Item 7.   Identification and Classification of the Subsidiary Which Acquired
the Security Being Reported on By the Parent Holding Company

          If a parent holding company has filed this schedule, pursuant to
Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit
stating the identity and the Item 3 classification of the relevant
subsidiary.  If a parent holding company has filed this schedule pursuant
to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the
identification of the relevant subsidiary.

Item 8.   Identification and Classification of Memebers of the Group

          If a group has filed this schedule pursuant to Section 240.13d-
1(b)(1)(ii)(J), so indicate under Item 3(j) and attach an exhibit stating
the identity and Item 3 classification of each memeber group.  If a group
has filed this schedule pursuant to Section 240.13d-1(c) or Section
240.13d-1(d), attach an exhibit stating the identity of each member group.

Item 9.   Notice of Dissolution of Group

          Notice of dissolution of a group may be furnished as an exhibit
stating the date of the dissolution and that all further filings with
respect to transactions in the security reported on will be filed, if
required, by members of the group, in their individual capacity.  See item 5

Item 10.  Certification

          (a)  The following certification shall be included if the
          statement is filed pursuant to Section 240.13d-1(b):

          By signing below I certify that, to the best of my knowledge and
          belief, the securities referred to above were not acquired and are
          not held in the ordinary course of business and were not acquired
          and are not held for the purpose of or with the effect of changing
          or influencing the control of the issuer of the securites and
          were not acquired and are not held in connection with or as a
          participant in any transaction having that purpose or effect.

          (b)  The following certification shall be included if the
          statement is filed pursuant to Section 240.13d-1(c):


          By signing below I certify that to the best of my knowledge and
          belief, the securities referred to above were not acquired and are
          not held for the purpose of or with the effect of changing or
          influencing the control of the issuer of the securities and were
          not acquired and are not held in connection with or as a
          participant in any transaction having that purpose or effect.

                            SIGNATURE

     After reasonable inquiry and to the best of my knowledge and
belief, the undersigned certifies that the information set forth
in this statement is true, complete and correct.

Date: JANUARY 26, 2012
                                   /s/ JOSEPH L. HARROSH