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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM N-CSR

                   CERTIFIED SHAREHOLDER REPORT OF REGISTERED
                        MANAGEMENT INVESTMENT COMPANIES



		Investment Company Act file number 811-21409

                Pioneer Municipal High Income Advantage Trust
               (Exact name of registrant as specified in charter)


                       60 State Street, Boston, MA 02109
              (Address of principal executive offices) (ZIP code)


            Dorothy E. Bourassa, Pioneer Investment Management, Inc.,
                       60 State Street, Boston, MA 02109
                    (Name and address of agent for service)


Registrant's telephone number, including area code:  (617) 742-7825


Date of fiscal year end:  March 31


Date of reporting period:  April 1, 2009 through September 30, 2009


Form N-CSR is to be used by management investment companies to file reports with
the Commission not later than 10 days after the transmission to stockholders of
any report that is required to be transmitted to stockholders under Rule 30e-1
under the Investment Company Act of 1940 (17 CFR 270.30e-1).  The Commission may
use the information provided on Form N-CSR in its regulatory, disclosure review,
inspection, and policymaking roles.

A registrant is required to disclose the information specified by Form N-CSR,
and the Commission will make this information public. A registrant is not
required to respond to the collection of information contained in Form N-CSR
unless the Form displays a currently valid Office of Management and Budget
("OMB") control number. Please direct comments concerning the accuracy of the
information collection burden estimate and any suggestions for reducing the
burden to Secretary, Securities and Exchange Commission, 450 Fifth Street, NW,
Washington, DC 20549-0609.  The OMB has reviewed this collection of information
under the clearance requirements of 44 U.S.C. ss. 3507.


ITEM 1. REPORTS TO SHAREOWNERS.


                    Pioneer Municipal High
                    Income Advantage Trust
--------------------------------------------------------------------------------
                    Semiannual Report | September 30, 2009
--------------------------------------------------------------------------------



                    Ticker Symbol:  MAV





                    [LOGO] PIONEER
                           Investments(R)






                        visit us: pioneerinvestments.com






Table of Contents


                                                                        
Letter to Shareowners                                                       2

Portfolio Management Discussion                                             4

Portfolio Summary                                                           7

Prices and Distributions                                                    8

Performance Update                                                          9

Schedule of Investments                                                    10

Financial Statements                                                       21

Notes to Financial Statements                                              26

Trustees, Officers and Service Providers                                   35


Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09    1


President's Letter

Dear Shareowner,

Stock and bond markets around the globe have begun to recover this year from
one of their most tumultuous periods in history. This is a welcome relief, and
we are generally optimistic about the prospects for the economy going forward.
Still, challenges remain. Unemployment is high. Consumer demand and loan growth
are weak. And housing has not yet returned to normal.

At Pioneer, we have long advocated the benefits of investing for the long term.
This strategy has generally performed well for many investors. Those who
remained invested in the market during the downturn have most likely seen their
portfolios start to recover this year as the Dow Jones Industrial Average
climbed back towards the 10,000 level. Many bond investors have similarly seen
a strong rebound, with a broad-based recovery across many different fixed-income
asset classes. The riskiest asset classes, such as high-yield bonds,
outperformed other fixed-income asset classes through the first eight months of
2009.

At Pioneer, we are not changing the approach to investing that we have used for
more than 80 years. We remain focused on company fundamentals and risk
management. Our investment process is based on careful research into individual
companies, quantitative analysis, and active portfolio management. This
three-pillared process, which we apply to each of our portfolios, is supported
by an integrated team approach and is designed to carefully balance risk and
reward. While we see potential opportunities for making money in many corners
of the markets around the globe, it takes research and experience to separate
solid investment opportunities from speculation.

Following this difficult period, many investors are rethinking their approach
to investing and risk management. Some are questioning whether the basic
investment principles they were taught in the past are still useful in today's
markets. Complicating matters is that financial markets remain unpredictable.
Our advice, as always, is to work closely with a trusted financial advisor to
discuss your goals and work together to develop an investment strategy that
meets your individual needs. There is no single best strategy that works for
every investor.

2    Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


We invite you to learn more about Pioneer and our time-tested approach to
investing by consulting with your financial advisor or visiting us online at
www.pioneerinvestments.com. We greatly appreciate you putting your trust in us
and we thank you for investing with Pioneer.

Respectfully,

/s/ Daniel K. Kingsbury
-----------------------
Daniel K. Kingsbury
President and CEO
Pioneer Investment Management USA, Inc.

Any information in this shareowner report regarding market or economic trends
or the factors influencing the Trust's historical or future performance are
statements of the opinion of Trust management as of the date of this report.
These statements should not be relied upon for any other purposes. Past
performance is no guarantee of future results, and there is no guarantee that
market forecasts discussed will be realized.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09    3


Portfolio Management Discussion | 9/30/09

Municipal bond investors were rewarded with relatively strong performance over
the past six months, as the municipal bond market recovered from one of the
most turbulent periods in history. In the following interview, David Eurkus,
who is responsible for the daily management of Pioneer Municipal High Income
Advantage Trust, discusses some of the factors that had an impact on the
municipal bond market and the Trust during the six months ended September 30,
2009.

Q  How did the Trust perform over the six months that ended September 30, 2009?

A  For the six-month period that ended September 30, 2009, Pioneer Municipal
   High Income Advantage Trust produced a total return of 37.00% at net asset
   value and 41.15% at market price, and Trust shares were selling at a 0.9%
   premium of market price to net asset value at September 30, 2009. Over the
   same period, the Barclays Capital (formerly Lehman Brothers) Municipal Bond
   Index, which tracks the performance of investment-grade bonds, returned
   9.38%, and the Barclays Capital High Yield Municipal Bond Index, which
   tracks the performance of below-investment-grade bonds, returned 23.33%. On
   September 30, 2009, the Trust held 141 issues in 34 states, territories and
   the District of Columbia and the average credit quality of the portfolio
   was BBB+.

   During the six-month period, investors earned a relatively high level of
   dividend income. The Trust's 30-day SEC yield was 9.74% on September 30,
   2009, and its current dividend yield based on market close was 7.86%. This
   translates into a taxable equivalent yield of 12.09%, based on the maximum
   Federal income tax rate of 35%. About 25% of the Trust's investments were
   subject to the Federal Alternative Minimum Tax (AMT).

Q  What was the investment environment like during the six months ended
   September 30, 2009?

A  After weathering one of the most difficult periods in history, the municipal
   bond market staged a dramatic rally over the past six months, as investors
   moved out of low-yielding, tax-exempt money market funds and sought the
   higher yields that tax-exempt bonds can provide. The substantial increase
   in investor demand came at a time when there was a sharp reduction in newly
   issued tax-exempt bonds, as roughly one-third of new municipal bonds were
   taxable "Build America Bonds," which are subsidized by the U.S. Treasury.
   The reduction in supply and robust demand for tax-exempt bonds benefited
   both the investment-grade and high-yield areas of the tax-exempt market
   during the six months ended September 30, 2009.

4    Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


Q  How did you manage the Trust during the six months ended September 30, 2009?

A  We did not make any material changes to the portfolio during the period. As
   has been the case in the past, the Trust was invested primarily in sectors
   that underpin the U.S. economy. At 32.4% of the total investment portfolio,
   health care was the biggest sector position in the Trust as of September
   30, 2009. Tobacco also was a relatively large position, at 11.5% of total
   investment portfolio, and airport bonds accounted for about 11.4% of total
   investment portfolio. The Trust also had investments in housing, pollution
   control, public power and water & sewer bonds. Below-investment-grade
   securities accounted for 50% of the Trust's total investments based on S&P,
   and investment-grade securities accounted for 50% of the Trust's total
   investments based on S&P.

Q  What investments most affected the Trust's performance during the six months
   ended September 30, 2009?

A  While both high-yield and investment-grade bonds contributed to returns, the
   Trust's position in the high-yield sector gave performance its biggest
   boost. The performance of the Trust's investment-grade tobacco bonds, whose
   prices had declined substantially in the first quarter of 2009, was also
   noteworthy. Airline bonds also fared well. The airline industry has been
   one of the hardest-hit areas of the economy, and prices of airline bonds
   experienced sharp declines. By cutting costs, reducing the number of
   flights and raising ticket prices, some airlines are now on a more stable
   footing, and investors bid up the prices of their bonds during the
   six-month period ended September 30, 2009. American Airlines and
   Continental Airlines are examples of carriers that benefited from
   investors' increased appetite for airline bonds. The Trust's substantial
   weight in lower-quality bonds in the health care sector also was a key
   contributor to benchmark-relative outperformance during the six-month
   period. As bond prices rose, the Trust's relatively long duration
   (sensitivity to changes in interest rates) also aided its return. One
   negative for the Trust's benchmark-relative performance during the period
   was its holdings in AAA-rated, pre-refunded/escrow-to-maturity (ETM)
   securities. While the performance of these securities was positive overall,
   they fell short of the benchmarks' returns.

Q  What is your outlook?

A  The tax-exempt municipal market has had a substantial run-up, and while we
   believe it may moderate, we continue to be constructive in our outlook for
   municipal bonds and the Trust; the investment environment for the Trust
   remains positive. We believe the economy is improving modestly. Inflation
   has remained benign, and the Federal Reserve Board appears to be holding
   interest rates within the 0.00% to 0.25% range. As we look ahead, we
   believe that municipal bonds have the potential to continue providing a

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09    5


   relatively high level of tax-free income -- and healthy returns -- for
   appropriate investors.

Please refer to the Schedule of Investments on pages 10-20 for a full listing
of Trust securities.

Investments in high-yield or lower-rated securities are subject to
greater-than-average risk. The Trust may invest in securities of issuers that
are in default or that are in bankruptcy.

A portion of income may be subject to state, federal, and/or alternative
minimum tax. Capital gains, if any, are subject to a capital gains tax. When
interest rates rise, the prices of fixed-income securities in the Trust will
generally fall. Conversely, when interest rates fall, the prices of
fixed-income securities in the Trust will generally rise. By concentrating in
municipal securities, the portfolio is more susceptible to adverse economic,
political or regulatory developments than is a portfolio that invests more
broadly. Investments in the Trust are subject to possible loss due to the
financial failure of underlying securities and their inability to meet their
debt obligations.

The Trust may use leverage through the issuance of preferred shares. Leverage
creates significant risks, including the risk that the Trust's income or
capital appreciation will not be sufficient to cover the cost of leverage,
which may adversely affect the return for the holders of common shares.

The Trust is required to maintain certain regulatory and rating agency asset
coverage requirements in connection with its outstanding preferred shares. In
order to maintain required asset coverage levels, the Trust may be required to
alter the composition of its investment portfolio or take other actions, such
as redeeming preferred shares with the proceeds from portfolio transactions, at
what might be inopportune times in the market. Such actions could reduce the
net earnings or returns to holders of the Trust's common shares over time.

Risks of investing in the Trust are discussed in greater detail in the Trust's
registration statement on Form N-2 relating to its common shares.

Past performance is no guarantee of future results, and there is no guarantee
that market forecasts discussed will be realized.

Any information in this shareowner report regarding market or economic trends
or the factors influencing the Trust's historical or future performance are
statements of the opinion of Trust management as of the date of this report.
These statements should not be relied upon for any other purposes.

6    Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


Portfolio Summary | 9/30/09

Portfolio Diversification
--------------------------------------------------------------------------------
(As a percentage of total investment portfolio)

[THE FOLLOWING DATA WAS REPRESENTED AS A PIE CHART IN THE PRINTED MATERIAL]


                           
Health Revenue                32.4%
Insured                       11.7
Tobacco Revenue               11.5
Airport Revenue               11.4
Pollution Control Revenue      8.8
Other Revenue                  6.8
Development Revenue            5.2
Housing Revenue                2.9
Transportation Revenue         2.6
Facilities Revenue             1.8
Water Revenue                  1.2
Education Revenue              1.2
Utilities Revenue              1.2
Power Revenue                  1.1
Airlines Revenue               0.2


Portfolio Maturity
--------------------------------------------------------------------------------
(As a percentage of long-term holdings)

[THE FOLLOWING DATA WAS REPRESENTED AS A PIE CHART IN THE PRINTED MATERIAL]


                           
0-1 year                       4.9%
1-3 years                     16.1
3-6 years                     19.9
6-8 years                     12.3
8-10 years                    12.6
10+ years                     34.2


Quality Distribution
--------------------------------------------------------------------------------
(As a percentage of total investment portfolio; based on S&P ratings)

[THE FOLLOWING DATA WAS REPRESENTED AS A PIE CHART IN THE PRINTED MATERIAL]


                           
AAA                           16.0%
AA                             3.7
A                              3.7
BBB                           26.6
BB                             6.5
B                              8.0
CCC                            4.5
CC                             0.1
C                              1.0
Not Rated                     29.9


The portfolio is actively managed and current holdings may be different.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09    7


Prices and Distributions | 9/30/09

Share Prices and Distributions
--------------------------------------------------------------------------------

Market Value per Common Share
--------------------------------------------------------------------------------



--------------------------------------------------------------------------------
                  9/30/09                       3/31/09
--------------------------------------------------------------------------------
                                              
                  $12.22                         $9.04
--------------------------------------------------------------------------------


Net Asset Value per Common Share
--------------------------------------------------------------------------------



--------------------------------------------------------------------------------
                  9/30/09                       3/31/09
--------------------------------------------------------------------------------
                                             
                  $12.11                         $9.23
--------------------------------------------------------------------------------


Distributions per Common Share
--------------------------------------------------------------------------------



--------------------------------------------------------------------------------
                                Net
                             Investment      Short-Term         Long-Term
                               Income       Capital Gains     Capital Gains
--------------------------------------------------------------------------------
                                                          
4/1/09-9/30/09                $0.4550           $ --               $ --
--------------------------------------------------------------------------------


10 Largest Holdings
--------------------------------------------------------------------------------
(As a percentage of long-term holdings)*


                                                                               
 1.    New Jersey Economic Development Authority Revenue, 6.25%, 9/15/29             2.87%
------------------------------------------------------------------------------------------
 2.    University of California, RIB, 12.821%, 5/15/38                               2.74
------------------------------------------------------------------------------------------
 3.    Massachusetts Housing Finance Agency, 5.35%, 12/1/45                          2.47
------------------------------------------------------------------------------------------
 4.    North Texas Tollway Authority Revenue, 5.75%, 1/1/33                          2.47
------------------------------------------------------------------------------------------
 5.    Indiana State Development Finance Authority Revenue, 5.75%, 10/1/11           2.34
------------------------------------------------------------------------------------------
 6.    Houston Texas Airport System Special Facilities Revenue, 6.75%, 7/1/29        2.34
------------------------------------------------------------------------------------------
 7.    Non-Profit Preferred Funding Trust I, Series E, 12.0%, 9/15/37 (144A)         2.30
------------------------------------------------------------------------------------------
 8.    Tobacco Settlement Financing Corp., 5.875%, 5/15/39                           2.18
------------------------------------------------------------------------------------------
 9.    California State Various Purpose, RIB, 11.118%, 6/1/37 (144A)                 2.15
------------------------------------------------------------------------------------------
10.    South Carolina Jobs Economic Development Authority Revenue, 6.375%, 8/1/34    2.00
------------------------------------------------------------------------------------------


* This list excludes temporary cash and derivative investments. The portfolio
  is actively managed, and currently holdings may be different. The holdings
  listed should not be considered recommendations to buy or sell any security
  listed.

8    Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


Performance Update | 9/30/09

Investment Returns
--------------------------------------------------------------------------------
The mountain chart on the right shows the change in market value, including
reinvestment of dividends and distributions, of a $10,000 investment made in
common shares of Pioneer Municipal High Income Advantage Trust, compared to
that of the Barclays Capital Municipal Bond Index and Barclays Capital High
Yield Municipal Bond Index.


Cumulative Total Returns
(As of September 30, 2009)
--------------------------------------------------------------------------------
                              Net Asset           Market
Period                        Value               Price
--------------------------------------------------------------------------------
                                            
Life-of-Trust
(10/20/03)                    29.07%              24.43%
5 Years                       25.44               24.88
1 Year                        15.55               29.69
--------------------------------------------------------------------------------


[THE FOLLOWING DATA WAS REPRESENTED AS A MOUNTAIN CHART IN THE PRINTED MATERIAL]

Value of $10,000 Investment



        Pioneer Municipal High         Barclays Capital          Barclays Capital High Yield
        Income Advantage Trust         Municipal Bond Index      Municipal Bond Index
                                                               
10/03         $10,000                       $10,000                     $10,000
 9/04         $ 9,965                       $10,513                     $10,098
 9/05         $11,335                       $10,939                      $9,875
 9/06         $12,310                       $11,425                     $10,101
 9/07         $13,392                       $11,779                     $10,116
 9/08         $ 9,595                       $11,559                      $9,517
 9/09         $12,443                       $13,275                     $10,956


Call 1-800-225-6292 or visit www.pioneerinvestments.com for the most recent
month-end performance results. Current performance may be lower or higher than
the performance data quoted.

Performance data shown represents past performance. Past performance is no
guarantee of future results. Investment return and market price will fluctuate,
and your shares may trade below net asset value ("NAV") due to such factors as
interest rate changes and the perceived credit quality of borrowers.

Total investment return does not reflect broker sales charges or commissions.
All performance is for common shares of the Trust.

Closed-end funds, unlike open-end funds, are not continuously offered. There is
a one-time public offering and, once issued, shares of closed-end funds are
sold in the open market through a stock exchange, and frequently trade at
prices lower than their NAV. NAV per common share is total assets less total
liabilities, which includes preferred shares divided by the number of common
shares outstanding.

When NAV is lower than market price, dividends are assumed to be reinvested at
the greater of NAV or 95% of the market price. When NAV is higher, dividends
are assumed to be reinvested at prices obtained under the Trust's dividend
reinvestment plan.

The performance table and graph do not reflect the deduction of fees and taxes
that a shareowner would pay on Trust distributions or the sale of Trust shares.

Index comparison begins October 31, 2003. The Barclays Capital Municipal Bond
Index is a broad measure of the municipal bond market. Barclays Capital High
Yield Municipal Bond Index totals over $26 billion in market value and
maintains over 1300 securities. Municipal bonds in this index have the
following requirements: maturities of one year or greater, sub investment grade
(below Baa or non-rated), fixed coupon rate, issue date later than 12/31/90,
deal size over $20 million, maturity size of at least $3 million. Index returns
are calculated monthly, assume reinvestment of dividends and, unlike Trust
returns, do not reflect any fees, expenses or sales charges. The indices are
not leveraged. You cannot invest directly in the Indices.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09    9


Schedule of Investments | 9/30/09 (unaudited)



---------------------------------------------------------------------------------------------------------
                      S&P/Moody's
  Principal           Ratings
  Amount             (unaudited)                                                             Value
---------------------------------------------------------------------------------------------------------
                                                                                    
                                   TAX-EXEMPT OBLIGATIONS -- 146.5% of Net Assets
                                   Arizona -- 3.3%
  $   5,000,000          NR/NR     Casa Grande Industrial Development Authority, Hospital
                                   Revenue, 7.625%, 12/1/29                                  $  4,513,100
      1,531,000         NR/Baa3    Pima County Industrial Development Authority,
                                   6.75%, 7/1/31                                                1,386,565
      2,640,000          NR/NR     Pima County Industrial Development Authority,
                                   7.0%, 1/1/38                                                 2,340,202
      1,000,000          NR/NR     San Luis Facility Development Corp., 7.25%, 5/1/27             898,570
                                                                                             ------------
                                                                                             $  9,138,437
---------------------------------------------------------------------------------------------------------
                                   California -- 14.9%
      3,140,000(a)      AAA/NR     California State University Revenue, RIB, 11.489%,
                                   11/1/39 (144A)                                            $  3,611,691
      2,425,000         A/Baa1     California State Various Purpose, 5.75%, 4/1/31              2,606,802
      8,575,000(a)      AAA/NR     California State Various Purpose, RIB, 11.118%,
                                   6/1/37 (144A)                                                8,993,631
      6,000,000          NR/NR     California Statewide Communities Development
                                   Authority, 9.0%, 12/1/38                                     4,950,180
      2,680,000+        AAA/Aaa    Golden State Tobacco Securitization Corp.,
                                   6.75%, 6/1/39                                                3,168,832
      2,500,000          A/A2      San Jose California Airport Revenue, 5.0%, 3/1/37            2,455,950
     10,500,000(a)      AAA/NR     University of California, RIB, 12.821%, 5/15/38             11,431,875
      7,670,000          C/NR      Valley Health System Hospital Revenue,
                                   6.875%, 5/15/23                                              4,223,869
                                                                                             ------------
                                                                                             $ 41,442,830
---------------------------------------------------------------------------------------------------------
                                   Colorado -- 1.1%
      2,850,000+         NR/NR     Denver Health & Hospital Authority Healthcare Revenue,
                                   6.0%, 12/1/31                                             $  3,154,095
---------------------------------------------------------------------------------------------------------
                                   Connecticut -- 2.8%
      7,750,000        BBB/Baa1    Connecticut State Development Authority Revenue,
                                   5.75%, 11/1/37                                            $  7,784,255
---------------------------------------------------------------------------------------------------------
                                   District of Columbia -- 3.5%
      2,700,000        BBB/Baa3    District of Columbia Tobacco Settlement Financing Corp.,
                                   6.5%, 5/15/33                                             $  2,799,522
      6,825,000        BBB/Baa3    District of Columbia Tobacco Settlement Financing Corp.,
                                   6.75%, 5/15/40                                               6,871,410
                                                                                             ------------
                                                                                             $  9,670,932
---------------------------------------------------------------------------------------------------------
                                   Florida -- 3.8%
      4,500,000        BBB/Baa1    Hillsborough County Industrial Development Authority
                                   Pollution Control Revenue, 5.5%, 10/1/23                  $  4,577,040
      1,980,000          NR/NR     Hillsborough County Industrial Development Authority
                                   Pollution Control Revenue, 6.75%, 7/1/29                     1,831,757


The accompanying notes are an integral part of these financial statements.

10   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09




---------------------------------------------------------------------------------------------------------
                      S&P/Moody's
  Principal           Ratings
  Amount             (unaudited)                                                             Value
---------------------------------------------------------------------------------------------------------
                                                                                    
                                   Florida -- (continued)
  $  1,000,000         BBB/Baa3    Hillsborough County Industrial Development Authority
                                   Revenue, 8.0%, 8/15/32                                    $  1,128,900
       500,000           BB/NR     Miami Beach Health Facilities Authority,
                                   5.375%, 11/15/28                                               414,560
     2,500,000           A-/A2     Miami-Dade County Florida Aviation Revenue,
                                   5.5%, 10/1/41                                                2,621,725
                                                                                             ------------
                                                                                             $ 10,573,982
---------------------------------------------------------------------------------------------------------
                                   Georgia -- 3.9%
     5,210,000(a)       NR/Aa3     Atlanta Georgia Water and Wastewater Revenue, RIB,
                                   11.304%, 11/1/43 (144A)                                   $  5,570,688
     1,065,000           NR/B2     Effingham County Industrial Development Authority,
                                   6.5%, 6/1/31                                                 1,071,848
     3,360,000           NR/NR     Fulton County Residential Care Facilities, 7.0%, 7/1/29      2,555,448
     1,650,000           NR/NR     Savannah Georgia Economic Development Authority
                                   Revenue, 7.4%, 1/1/34                                        1,675,212
                                                                                             ------------
                                                                                             $ 10,873,196
---------------------------------------------------------------------------------------------------------
                                   Guam -- 1.9%
     4,500,000+         AAA/B2     Northern Mariana Islands, 6.75%, 10/1/33                  $  5,337,360
---------------------------------------------------------------------------------------------------------
                                   Idaho -- 1.8%
     2,000,000         BBB/Baa2    Power County Industrial Development Corp.,
                                   6.45%, 8/1/32                                             $  2,010,740
     3,000,000         BBB/Baa2    Power County Pollution Control Revenue,
                                   5.625%, 10/1/14                                              2,999,910
                                                                                             ------------
                                                                                             $  5,010,650
---------------------------------------------------------------------------------------------------------
                                   Illinois -- 5.8%
     3,000,000(b)        NR/NR     Centerpoint Intermodal Center, 10.0%, 6/15/23 (144A)      $  1,628,520
     3,000,000          AA-/Aa3    City of Chicago Illinois, 5.0%, 1/1/28                       3,130,380
     2,000,000          NR/Caa2    City of Chicago Illinois, 5.5%, 12/1/30                      1,414,580
     2,000,000          AAA/NR     Illinois Finance Authority Revenue, 6.0%, 8/15/25            2,104,760
     1,000,000           NR/NR     Illinois Finance Authority Revenue, 6.0%, 11/15/27             844,700
     2,000,000          AA+/Aa2    Illinois Finance Authority Revenue, 6.0%, 8/15/39            2,230,180
     2,500,000           NR/NR     Illinois Finance Authority Revenue, 6.125%, 11/15/25         2,270,575
     1,500,000(c)        NR/NR     Illinois Health Facilities Authority Revenue,
                                   6.9%, 11/15/33                                                 662,250
     2,700,000           NR/NR     Southwestern Illinois Development Authority Revenue,
                                   5.625%, 11/1/26                                              1,856,277
                                                                                             ------------
                                                                                             $ 16,142,222
---------------------------------------------------------------------------------------------------------
                                   Indiana -- 6.7%
    10,000,000          BBB/NR     Indiana State Development Finance Authority Revenue,
                                   5.75%, 10/1/11                                            $  9,775,500
     5,000,000           NR/B2     Jasper County Industrial Economic Development
                                   Revenue, 5.6%, 4/1/29                                        4,416,050


The accompanying notes are an integral part of these financial statements.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   11


Schedule of Investments | 9/30/09 (unaudited) (continued)



------------------------------------------------------------------------------------------------------------
                      S&P/Moody's
  Principal           Ratings
  Amount             (unaudited)                                                                Value
------------------------------------------------------------------------------------------------------------
                                                                                       
                                     Indiana -- (continued)
  $    2,500,000(b)      BBB/Baa2    Rockport Indiana Pollution Control Revenue,
                                     6.25%, 6/2/25                                              $  2,742,975
       2,085,000           NR/NR     Vincennes Industrial Economic Development Revenue,
                                     6.25%, 1/1/24                                                 1,654,510
                                                                                                ------------
                                                                                                $ 18,589,035
------------------------------------------------------------------------------------------------------------
                                     Kentucky -- 1.6%
         500,000          BB-/NR     Kentucky Economic Development Finance Authority
                                     Hospital System Revenue, 5.7%, 10/1/10                     $    500,710
       4,400,000          BB-/NR     Kentucky Economic Development Finance Authority
                                     Hospital System Revenue, 5.875%, 10/1/22                      3,858,052
                                                                                                ------------
                                                                                                $  4,358,762
------------------------------------------------------------------------------------------------------------
                                     Louisiana -- 6.5%
       2,500,000          BB/Ba3     Louisiana Local Government Environmental Facilities
                                     Development Authority Revenue, 6.75%, 11/1/32              $  2,418,750
       6,000,000           NR/A3     Louisiana Public Facilities Authority Revenue,
                                     5.5%, 5/15/47                                                 5,890,140
         750,000          BBB+/NR    Opelousas Louisiana General Hospital Authority
                                     Revenue, 5.75%, 10/1/23                                         763,343
       9,415,000         BBB/Baa3    Tobacco Settlement Financing Corp., 5.875%, 5/15/39           9,112,967
                                                                                                ------------
                                                                                                $ 18,185,200
------------------------------------------------------------------------------------------------------------
                                     Maryland -- 0.5%
         460,000           NR/NR     Maryland Health & Higher Educational Facilities Authority
                                     Revenue, 5.25%, 1/1/27                                     $    377,642
       1,250,000           NR/NR     Maryland Health & Higher Educational Facilities Authority
                                     Revenue, 5.3%, 1/1/37                                           880,638
                                                                                                ------------
                                                                                                $  1,258,280
------------------------------------------------------------------------------------------------------------
                                     Massachusetts -- 5.6%
       2,195,000         BBB-/Baa3   Massachusetts Health & Educational Facilities Authority
                                     Revenue, 5.375%, 7/15/28                                   $  1,907,609
       1,000,000+         NR/Baa3    Massachusetts Health & Educational Facilities Authority
                                     Revenue, 6.35%, 7/15/32                                       1,146,890
      10,760,000          AA-/Aa3    Massachusetts Housing Finance Agency,
                                     5.35%, 12/1/45                                               10,311,846
         830,000           BB/NR     Massachusetts Development Finance Agency,
                                     5.25%, 10/1/18                                                  720,631
       1,955,000           NR/NR     Massachusetts Development Finance Agency,
                                     7.1%, 7/1/32                                                  1,522,632
                                                                                                ------------
                                                                                                $ 15,609,608
------------------------------------------------------------------------------------------------------------


The accompanying notes are an integral part of these financial statements.

12   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09




------------------------------------------------------------------------------------------------------------
                      S&P/Moody's
  Principal           Ratings
  Amount             (unaudited)                                                                Value
------------------------------------------------------------------------------------------------------------
                                                                                       
                                     Michigan -- 3.5%
   $   1,500,000+         AAA/A3     Delta County Michigan Economic Development Corp.,
                                     6.25%, 4/15/27                                             $  1,695,795
       3,000,000+          NR/NR     Macomb County Hospital Finance Authority Revenue,
                                     5.875%, 11/15/34                                              3,519,750
         745,000           NR/NR     Michigan Public Educational Facilities Authority Revenue,
                                     7.0%, 10/1/36                                                   660,837
       4,130,000          BB-/Ba3    Michigan State Hospital Finance Authority Revenue,
                                     5.5%, 8/15/23                                                 3,100,928
       1,000,000           NR/NR     Michigan State Strategic Fund Solid Waste Disposal
                                     Revenue, 7.375%, 1/15/22                                        819,320
                                                                                                ------------
                                                                                                $  9,796,630
------------------------------------------------------------------------------------------------------------
                                     Missouri -- 1.1%
       1,850,000           NR/NR     Kansas City Industrial Development Authority Revenue,
                                     5.875%, 1/1/37 (144A)                                      $  1,475,986
       1,500,000(c)        NR/Ca     St. Louis Industrial Development Authority Revenue,
                                     7.2%, 12/15/28                                                  284,250
       6,640,000(c)        NR/Ca     St. Louis Industrial Development Authority Revenue,
                                     7.25%, 12/15/35                                               1,257,815
                                                                                                ------------
                                                                                                $  3,018,051
------------------------------------------------------------------------------------------------------------
                                     Montana -- 0.5%
       2,445,000(d)        NR/NR     Hardin Increment Industrial Infrastructure Development
                                     Revenue, 0.0%, 9/1/31                                      $  1,228,417
       1,000,000(c)        NR/NR     Two Rivers Authority, Inc., Project Revenue,
                                     7.375%, 11/1/27                                                 161,370
                                                                                                ------------
                                                                                                $  1,389,787
------------------------------------------------------------------------------------------------------------
                                     Nevada -- 2.3%
       1,500,000           A/A2      Henderson Nevada Health Care Facilities Revenue,
                                     5.625%, 7/1/24                                             $  1,564,200
       1,600,000(c)        NR/NR     Nevada State Department of Business & Industry,
                                     7.25%, 1/1/23                                                    80,000
       1,000,000(c)        NR/NR     Nevada State Department of Business & Industry,
                                     7.375%, 1/1/30                                                   50,000
       1,320,000(c)        NR/NR     Nevada State Department of Business & Industry,
                                     7.375%, 1/1/40                                                   66,000
       5,000,000           A-/A3     Reno Nevada Hospital Revenue, 5.25%, 6/1/41                   4,542,700
                                                                                                ------------
                                                                                                $  6,302,900
------------------------------------------------------------------------------------------------------------
                                     New Hampshire -- 0.4%
       1,125,000           NR/NR     New Hampshire Health & Educational Facilities Authority
                                     Revenue, 5.875%, 7/1/34                                    $  1,080,281
------------------------------------------------------------------------------------------------------------


The accompanying notes are an integral part of these financial statements.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   13


Schedule of Investments | 9/30/09 (unaudited) (continued)



--------------------------------------------------------------------------------------------------------
                      S&P/Moody's
  Principal           Ratings
  Amount             (unaudited)                                                            Value
--------------------------------------------------------------------------------------------------------
                                                                                   
                                   New Jersey -- 12.6%
  $  2,500,000           NR/NR     Burlington County New Jersey Bridge Commission
                                   Revenue, 5.625%, 1/1/38                                  $  2,041,025
    13,000,000           B/B3      New Jersey Economic Development Authority Revenue,
                                   6.25%, 9/15/29                                             11,998,740
     3,500,000(a)       NR/Aa3     New Jersey State Turnpike Authority, RIB, 12.492%,
                                   1/1/28 (144A)                                               5,478,935
    10,375,000          AAA/Aa1    New Jersey Transportation Trust Fund Authority Revenue,
                                   0.0%, 12/15/27                                              4,335,505
     1,000,000+         AAA/Aaa    Tobacco Settlement Financing Corp., 6.25%, 6/1/43           1,172,470
     3,250,000+         AAA/Aaa    Tobacco Settlement Financing Corp., 6.75%, 6/1/39           3,868,442
     5,000,000+         AAA/Aaa    Tobacco Settlement Financing Corp., 7.0%, 6/1/41            5,994,000
                                                                                            ------------
                                                                                            $ 34,889,117
--------------------------------------------------------------------------------------------------------
                                   New York -- 6.4%
     1,900,000           NR/NR     Dutchess County Industrial Development Agency,
                                   7.5%, 3/1/29                                             $  1,890,215
     1,000,000           NR/NR     Nassau County New York Industrial Development Agency
                                   Revenue, 6.7%, 1/1/43                                         913,700
     5,000,000          BB/Ba3     New York City Industrial Development Agency,
                                   5.25%, 12/1/32                                              3,572,050
     2,000,000         BBB/Baa1    New York City Industrial Development Agency,
                                   5.375%, 6/1/23                                              1,955,380
     3,950,000          BB/Ba3     New York City Industrial Development Agency,
                                   7.625%, 12/1/32                                             3,806,299
     5,000,000          AAA/Aaa    New York State Environmental Facilities Corp.,
                                   5.0%, 6/15/33                                               5,187,900
       500,000           NR/NR     Ulster County New York Industrial Development Agency,
                                   6.0%, 9/15/37                                                 419,835
                                                                                            ------------
                                                                                            $ 17,745,379
--------------------------------------------------------------------------------------------------------
                                   North Carolina -- 2.0%
     6,000,000           NR/NR     Charlotte North Carolina Special Facilities Revenue,
                                   7.75%, 2/1/28                                            $  5,445,720
--------------------------------------------------------------------------------------------------------
                                   Ohio -- 2.2%
     3,115,000           B-/NR     Belmont County Health System Revenue, 5.7%, 1/1/13       $  2,899,442
     1,000,000           B-/NR     Belmont County Health System Revenue, 5.8%, 1/1/18            811,840
     3,000,000          CCC+/B3    Cleveland Airport Special Revenue, 5.375%, 9/15/27          2,409,180
                                                                                            ------------
                                                                                            $  6,120,462
--------------------------------------------------------------------------------------------------------
                                   Oklahoma -- 2.8%
     1,500,000           BB/NR     Jackson County Memorial Hospital Authority Revenue,
                                   7.3%, 8/1/15                                             $  1,501,080
     2,220,000          B-/Caa2    Tulsa Municipal Airport Trust Revenue, 6.25%, 6/1/20        1,960,349
     1,500,000          B-/Caa2    Tulsa Municipal Airport Trust Revenue, 7.35%, 12/1/11       1,480,245
     3,000,000(b)       B-/Caa2    Tulsa Municipal Airport Trust Revenue, 7.75%, 6/1/35        2,910,540
                                                                                            ------------
                                                                                            $  7,852,214
--------------------------------------------------------------------------------------------------------


The accompanying notes are an integral part of these financial statements.

14   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09




-----------------------------------------------------------------------------------------------------------
                        S&P/Moody's
  Principal             Ratings
  Amount                (unaudited)                                                            Value
-----------------------------------------------------------------------------------------------------------
                                                                                      
                                     Pennsylvania -- 10.1%
   $   3,000,000+         AAA/NR     Allegheny County Hospital Development Authority
                                     Revenue, 9.25%, 11/15/22                                  $  3,352,320
         500,000+         AAA/NR     Allegheny County Hospital Development Authority
                                     Revenue, 9.25%, 11/15/30                                       558,720
       1,000,000          BBB-/NR    Clarion County Hospital Authority Revenue,
                                     5.625%, 7/1/21                                               1,001,270
       3,600,000           B-/NR     Columbia County Hospital Authority Revenue,
                                     5.85%, 6/1/24                                                3,228,300
         945,000          BBB/Ba2    Hazleton Health Services Authority Hospital Revenue,
                                     6.125%, 7/1/16                                                 910,300
       1,405,000          NR/Baa3    Montgomery County Higher Education & Health Authority
                                     Hospital Revenue, 6.6%, 7/1/10                               1,409,903
       1,430,000          BB+/NR     Pennsylvania Economic Development Financing Authority
                                     Revenue, 5.125%, 6/1/18                                      1,286,871
       1,805,000          BB+/NR     Pennsylvania Economic Development Financing Authority
                                     Revenue, 5.3%, 6/1/10                                        1,783,340
       2,330,000          BB+/NR     Pennsylvania Economic Development Financing Authority
                                     Revenue, 5.35%, 6/1/11                                       2,264,108
       5,000,000          B+/Caa1    Pennsylvania Economic Development Financing Authority
                                     Revenue, 6.0%, 6/1/31                                        3,831,200
       5,000,000         BBB/Baa3    Philadelphia Hospitals & Higher Education Facilities
                                     Authority Revenue, 5.0%, 7/1/34                              4,228,550
       2,005,000           B-/NR     Scranton-Lackawanna Health & Welfare Authority
                                     Revenue, 6.1%, 7/1/11                                        1,962,253
       2,245,000           B-/NR     Scranton-Lackawanna Health & Welfare Authority
                                     Revenue, 6.15%, 7/1/12                                       2,172,644
                                                                                               ------------
                                                                                               $ 27,989,779
-----------------------------------------------------------------------------------------------------------
                                     Rhode Island -- 3.3%
       1,385,000           NR/NR     Central Falls Rhode Island Detention Facilities Revenue,
                                     7.25%, 7/15/35                                            $  1,117,737
       8,285,000         BBB/Baa3    Tobacco Settlement Financing Corp., 6.25%, 6/1/42            8,170,584
                                                                                               ------------
                                                                                               $  9,288,321
-----------------------------------------------------------------------------------------------------------
                                     South Carolina -- 6.8%
       1,500,000           CC/NR     Connector 2000 Association, Inc., Toll Road Revenue,
                                     5.375%, 1/1/38                                            $    449,235
       7,140,000+        BBB+/Baa1   South Carolina Jobs Economic Development Authority
                                     Revenue, 6.375%, 8/1/34                                      8,360,726
         860,000+        BBB+/Baa1   South Carolina Jobs Economic Development Authority
                                     Revenue, 6.375%, 8/1/34                                      1,010,526
       3,000,000+         AAA/NR     South Carolina Jobs Economic Development Authority
                                     Revenue, 8.0%, 10/1/31                                       3,267,780
       4,400,000(e)      BBB/Baa3    Tobacco Settlement Revenue Management,
                                     6.375%, 5/15/30                                              5,677,716
                                                                                               ------------
                                                                                               $ 18,765,983
-----------------------------------------------------------------------------------------------------------


The accompanying notes are an integral part of these financial statements.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   15


Schedule of Investments | 9/30/09 (unaudited) (continued)



---------------------------------------------------------------------------------------------------------
                      S&P/Moody's
  Principal           Ratings
  Amount             (unaudited)                                                             Value
---------------------------------------------------------------------------------------------------------
                                                                                    
                                   Tennessee -- 3.7%
  $    1,000,000+        NR/A2     Johnson City Health & Educational Facilities Board
                                   Hospital Revenue, 7.5%, 7/1/33                            $  1,137,860
       7,000,000         NR/A1     Knox County Health Educational & Housing Facilities
                                   Board Hospital Revenue, 6.5%, 4/15/31                        7,213,220
       2,400,000        BBB+/NR    Sullivan County Health Educational and Housing
                                   Facilities Board Hospital Revenue, 5.25%, 9/1/36             1,966,008
                                                                                             ------------
                                                                                             $ 10,317,088
---------------------------------------------------------------------------------------------------------
                                   Texas -- 19.1%
       8,650,000       CCC/Caa3    Brazos River Authority Pollution Control Revenue,
                                   6.75%, 10/1/38                                            $  4,238,500
       4,000,000       CCC/Caa3    Brazos River Authority Pollution Control Revenue,
                                   7.7%, 4/1/33                                                 2,280,000
       7,350,000         NR/NR     Gulf Coast Industrial Development Authority,
                                   7.0%, 12/1/36                                                3,211,729
      10,000,000        CCC+/B3    Houston Texas Airport System Special Facilities Revenue,
                                   6.75%, 7/1/29                                                9,764,500
         960,000         NR/NR     IAH Public Facility Corp., Project Revenue Bonds, Series
                                   2006, 6.0%, 5/1/16                                             886,051
       1,000,000         NR/NR     IAH Public Facility Corp., Project Revenue Bonds, Series
                                   2006, 6.0%, 5/1/21                                             834,730
       1,350,000         NR/NR     IAH Public Facility Corp., Project Revenue Bonds, Series
                                   2006, 6.125%, 5/1/26                                         1,076,112
       2,750,000        AAA/Aa3    Lower Colorado River Authority, 5.0%, 5/15/31                2,810,197
         845,000         NR/NR     Lubbock Health Facilities Development Corp.,
                                   6.5%, 7/1/26                                                   767,268
       2,000,000         NR/NR     Lubbock Health Facilities Development Corp.,
                                   6.625%, 7/1/36                                               1,780,680
       7,750,000       BBB-/Ba1    Matagorda County Navigation District Number 1
                                   Revenue, 5.95%, 5/1/30                                       7,261,130
       9,750,000        BBB+/A3    North Texas Tollway Authority Revenue, 5.75%, 1/1/33        10,292,685
       1,711,000        NR/Aaa     Panhandle Regional Housing Finance Corp. Multifamily
                                   Housing Revenue, 6.6%, 7/20/31                               1,824,491
       1,000,000       BB+/Baa2    Richardson Hospital Authority Revenue, 6.0%, 12/1/34           897,480
       1,000,000         BB/NR     Texas Midwest Public Facility Corp. Revenue,
                                   9.0%, 10/1/30                                                1,048,370
       4,700,000        NR/Baa3    Tomball Hospital Authority, 6.0%, 7/1/25                     4,097,178
                                                                                             ------------
                                                                                             $ 53,071,101
---------------------------------------------------------------------------------------------------------
                                   Utah -- 0.5%
       1,600,000         NR/NR     Spanish Fork Charter School Revenue, 5.7%,
                                   11/15/36 (144A)                                           $  1,367,520
---------------------------------------------------------------------------------------------------------
                                   Virginia -- 0.8%
       2,000,000       BBB+/Baa1   Washington County Industrial Development Authority
                                   Revenue, 7.75%, 7/1/38                                    $  2,322,680
---------------------------------------------------------------------------------------------------------


The accompanying notes are an integral part of these financial statements.

16   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09




------------------------------------------------------------------------------------------------------------------
                              S&P/Moody's
  Principal                   Ratings
  Amount                     (unaudited)                                                             Value
------------------------------------------------------------------------------------------------------------------
                                                                                            
                                          Washington -- 3.4%
    $    1,195,000            BBB/Baa3    Tobacco Settlement Authority Revenue, 6.5%, 6/1/26         $   1,223,441
         2,000,000            BBB/Baa2    Washington State Health Care Facilities Authority,
                                          6.125%, 8/15/37                                                2,032,880
         2,000,000            BBB/Baa2    Washington State Health Care Facilities Authority,
                                          6.25%, 8/15/42                                                 2,038,380
         5,000,000              NR/NR     Washington State Housing Finance Commission
                                          Nonprofit Revenue Bonds, 5.625%, 1/1/27                        4,130,550
                                                                                                     -------------
                                                                                                     $   9,425,251
------------------------------------------------------------------------------------------------------------------
                                          Wisconsin -- 1.3%
         2,900,000              NR/NR     Aztalan Wisconsin Exempt Facilities Revenue,
                                          7.50%, 5/1/18                                              $     152,250
         1,000,000              NR/NR     Wisconsin State Health & Educational Facilities Authority
                                          Revenue, 6.125%, 4/1/24                                          915,550
         1,000,000              NR/NR     Wisconsin State Health & Educational Facilities Authority
                                          Revenue, 6.25%, 4/1/34                                           848,980
         1,500,000              A+/A1     Wisconsin State Health & Educational Facilities Authority
                                          Revenue, 6.625%, 2/15/39                                       1,640,595
                                                                                                     -------------
                                                                                                     $   3,557,375
------------------------------------------------------------------------------------------------------------------
                                          TOTAL TAX-EXEMPT OBLIGATIONS
                                          (Cost $410,429,304)                                        $ 406,874,483
------------------------------------------------------------------------------------------------------------------
                                          MUNICIPAL COLLATERALIZED DEBT OBLIGATION -- 3.4% of Net Assets
        13,000,000(b)(f)        NR/NR     Non-Profit Preferred Funding Trust I, Series E, 12.0%,
                                          9/15/37 (144A)                                             $   9,588,670
------------------------------------------------------------------------------------------------------------------
                                          TOTAL MUNICIPAL COLLATERALIZED
                                          DEBT OBLIGATION
                                          (Cost $13,000,000)                                         $   9,588,670
------------------------------------------------------------------------------------------------------------------
       Shares
------------------------------------------------------------------------------------------------------------------
                                          COMMON STOCK -- 0.4% of Net Assets
           109,625(g)                     Delta Airlines, Inc.                                       $     982,240
------------------------------------------------------------------------------------------------------------------
                                          TOTAL COMMON STOCK
                                          (Cost $3,210,349)                                          $     982,240
------------------------------------------------------------------------------------------------------------------
                                          TOTAL INVESTMENTS IN SECURITIES -- 150.3%
                                          (Cost $426,639,653) (h)(i)                                 $ 417,445,393
------------------------------------------------------------------------------------------------------------------
                                          OTHER ASSETS AND LIABILITIES 3.7%                          $  10,214,829
------------------------------------------------------------------------------------------------------------------
                                          PREFERRED SHARES AT REDEMPTION VALUE,
------------------------------------------------------------------------------------------------------------------
                                          INCLUDING DIVIDENDS PAYABLE -- (54.0)%                     $(150,006,364)
------------------------------------------------------------------------------------------------------------------
                                          NET ASSETS APPLICABLE TO COMMON
                                          SHAREOWNERS -- 100.0%                                      $ 277,653,858
==================================================================================================================


The accompanying notes are an integral part of these financial statements.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   17


Schedule of Investments | 9/30/09 (unaudited) (continued)

(144A) Security is exempt from registration under Rule 144A of the Securities
       Act of 1933. Such securities may be resold normally to qualified
       institutional buyers in a transaction exempt from registration. At
       September 30, 2009, the value of these securities amounted to
       $37,715,641, or 13.6% of total net assets applicable to common
       shareowners.

RIB    Residual Interest Bonds.

NR     Security not rated by S&P or Moody's.

+      Prerefunded bonds have been collateralized by U.S. Treasury or U.S.
       Government Agency securities which are held in escrow to pay interest and
       principal on the tax exempt issue and to retire the bonds in full at the
       earliest refunding date.

(a)    The interest rate is subject to change periodically and inversely based
       upon prevailing market rates. The rate shown is the coupon rate at
       September 30, 2009.

(b)    The interest rate is subject to change periodically. The interest rate
       shown is the rate at September 30, 2009.

(c)    Security is in default and is non-income producing.

(d)    Debt obligation initially issued at one coupon which converts to a higher
       coupon at a specific date. The rate shown is the coupon rate at September
       30, 2009.

(e)    Escrow to maturity.

(f)    Indicates a security that has been deemed illiquid. The aggregate cost of
       illiquid securities is $13,000,000. The aggregate value is $9,588,670, or
       3.5% of the total net assets applied to common shareowners.

(g)    Non-income producing.

The accompanying notes are an integral part of these financial statements.

18   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


(h)    The concentration of investments by type of obligation/market sector is
       as follows:


                                                
          Insured
            FSA                                      8.2%
            AMBAC                                    1.3
            MBIA                                     1.0
            ASSURED GTY                              0.5
            ACA                                      0.5
            Q-SBLF                                   0.2
          Revenue Bonds:
            Health Revenue                          32.5
            Tobacco Revenue                         11.5
            Airport Revenue                         11.4
            Pollution Control Revenue                8.8
            Other Revenue                            6.8
            Development Revenue                      5.2
            Housing Revenue                          2.9
            Transportation Revenue                   2.6
            Facilities Revenue                       1.8
            Water Revenue                            1.3
            Education Revenue                        1.2
            Utilities Revenue                        1.2
            Power Revenue                            1.1
                                                   -----
                                                   100.0%
                                                   =====


(i)    At September 30, 2009, the net unrealized loss on investments based on
       cost for federal income tax purposes of $421,950,983 was as follows:


                                                                  
          Aggregate gross unrealized gain for all investments
            in which there is an excess of value over tax cost       $41,979,769
          Aggregate gross unrealized loss for all investments
            in which there is an excess of tax cost over value       (46,485,359)
                                                                     -----------
          Net unrealized loss                                        $(4,505,590)
                                                                     ===========


For financial reporting purposes net unrealized loss on investments was
$9,194,260 and cost of investments aggregated $426,639,653.

Purchases and sales of securities (excluding temporary cash investments) for
the period ended September 30, 2009, aggregated $19,411,648 and $11,009,869,
respectively.

The accompanying notes are an integral part of these financial statements.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   19


Schedule of Investments | 9/30/09 (unaudited) (continued)

Various inputs are used in determining the value of the Trust's investments.
These inputs are summarized in the three broad levels listed below.

Highest priority is given to Level 1 inputs and lowest priority is given to
Level 3.


             
  Level 1 -- quoted prices in active markets for identical securities
  Level 2 -- other significant observable inputs (including quoted prices for
             similar securities, interest rates, prepayment speeds, credit
             risk, etc.)
  Level 3 -- significant unobservable inputs (including the Trust's own
             assumptions in determining fair value of investments)


The following is a summary of the inputs used as of September 30, 2009, in
valuing the Trust's investments:



--------------------------------------------------------------------------------------------------
                                              Level 1        Level 2       Level 3       Total
--------------------------------------------------------------------------------------------------
                                                                          
Tax-exempt obligations                       $     --     $406,874,483      $  --     $406,874,483
Municipal collateralized debt obligation           --        9,588,670         --        9,588,670
Common stock                                  982,240               --         --          982,240
--------------------------------------------------------------------------------------------------
  Total                                      $982,240     $416,463,153      $  --     $417,445,393
==================================================================================================


The accompanying notes are an integral part of these financial statements.

20   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


Statement of Assets and Liabilities | 9/30/09 (unaudited)


                                                                         
ASSETS:
  Investments in securities, at value (cost $426,639,653)                $417,445,393
  Cash                                                                        772,760
  Receivables --
     Investment securities sold                                               170,000
     Interest                                                               9,439,264
     Reinvestment of distributions                                            124,563
  Prepaid expenses                                                             43,440
-------------------------------------------------------------------------------------
     Total assets                                                        $427,995,420
-------------------------------------------------------------------------------------
LIABILITIES:
  Due to affiliates                                                      $    212,519
  Administration fee payable                                                   23,613
  Accrued expenses                                                             99,066
-------------------------------------------------------------------------------------
     Total liabilities                                                   $    335,198
--------------------------------------------------------------------------------------
PREFERRED SHARES AT REDEMPTION VALUE:
  $25,000 liquidation value per share applicable to 6,000 shares,
   including dividends payable of $6,364                                 $150,006,364
-------------------------------------------------------------------------------------
NET ASSETS APPLICABLE TO COMMON SHAREOWNERS:
  Paid-in capital                                                        $325,992,583
  Undistributed net investment income                                      11,760,710
  Accumulated net realized loss on investments and interest rate swaps    (50,905,175)
  Net unrealized loss on investments                                       (9,194,260)
-------------------------------------------------------------------------------------
     Net assets applicable to common shareowners                         $277,653,858
=====================================================================================
NET ASSET VALUE PER SHARE:
No par value, (unlimited number of shares authorized)
  Based on $277,653,858/22,932,807 common shares                         $      12.11
=====================================================================================


The accompanying notes are an integral part of these financial statements.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   21


Statement of Operations (unaudited)

For the Six Months Ended 9/30/09


                                                                              
INVESTMENT INCOME:
  Interest                                                                          $15,688,671
------------------------------------------------------------------------------------------------
EXPENSES:
  Management fees                                                  $  1,156,550
  Administrative fees                                                   205,382
  Transfer agent fees and expenses                                       20,241
  Auction agent fees                                                    195,968
  Custodian fees                                                          7,227
  Registration fees                                                      11,908
  Professional fees                                                      74,652
  Printing expense                                                       18,541
  Trustees' fees                                                          7,169
  Pricing fees                                                            9,759
  Miscellaneous                                                          17,756
------------------------------------------------------------------------------------------------
     Total expenses                                                                 $ 1,725,153
------------------------------------------------------------------------------------------------
       Net investment income                                                        $13,963,518
------------------------------------------------------------------------------------------------
REALIZED AND UNREALIZED GAIN (LOSS) ON INVESTMENTS AND
INTEREST RATE SWAPS:
  Net realized loss from:
   Investments                                                     $ (1,893,055)
   Interest rate swaps                                                 (135,950)    $(2,029,005)
------------------------------------------------------------------------------------------------
  Change in net unrealized loss from:
   Investments                                                     $ 64,816,586
   Interest rate swaps                                                  131,406     $64,947,992
------------------------------------------------------------------------------------------------
       Net gain on investments and interest rate swaps                              $62,918,987
------------------------------------------------------------------------------------------------
DISTRIBUTIONS TO PREFERRED SHAREOWNERS FROM NET
INVESTMENT INCOME                                                                   $  (518,696)
------------------------------------------------------------------------------------------------
  Net increase in net assets applicable to common shareowners
   resulting from operations                                                        $76,363,809
================================================================================================


The accompanying notes are an integral part of these financial statements.

22   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


Statement of Changes in Net Assets

For the Six Months Ended 9/30/09 and the Year Ended 3/31/09, respectively



-------------------------------------------------------------------------------------------------
                                                                Six Months Ended
                                                                9/30/09             Year Ended
                                                               (unaudited)          3/31/09
-------------------------------------------------------------------------------------------------
                                                                              
FROM OPERATIONS:
Net investment income                                           $ 13,963,518        $ 27,756,168
Net realized loss on investments and interest rate swaps          (2,029,005)        (30,870,281)
Change in net unrealized loss on investments and
  interest rate swaps                                             64,947,992         (70,216,736)
Distributions to preferred shareowners from net
  investment income                                                 (518,696)         (4,573,950)
-------------------------------------------------------------------------------------------------
   Net increase (decrease) in net assets applicable to
     common shareowners resulting from operations               $ 76,363,809        $(77,904,799)
-------------------------------------------------------------------------------------------------
DISTRIBUTIONS TO COMMON SHAREOWNERS:
Net investment income
  ($0.455 and $0.900 per share, respectively)                   $(10,418,906)       $(20,552,506)
-------------------------------------------------------------------------------------------------
   Total distributions to common shareowners                    $(10,418,906)       $(20,552,506)
-------------------------------------------------------------------------------------------------
FROM TRUST SHARE TRANSACTIONS:
Reinvestment of distributions                                   $    562,083        $  1,103,907
-------------------------------------------------------------------------------------------------
   Net increase in net assets applicable to common
     shareowners resulting from Trust share transactions        $    562,083        $  1,103,907
-------------------------------------------------------------------------------------------------
   Net increase (decrease) in net assets applicable to
     common shareowners                                         $ 66,506,986        $(97,353,398)
NET ASSETS APPLICABLE TO COMMON SHAREOWNERS:
Beginning of period                                              211,146,872         308,500,270
-------------------------------------------------------------------------------------------------
End of period                                                   $277,653,858        $211,146,872
=================================================================================================
Undistributed net investment income                             $ 11,760,710        $  8,734,794
=================================================================================================


The accompanying notes are an integral part of these financial statements.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   23


Financial Highlights



----------------------------------------------------------------------------------------------------------------------------------
                                                            Six Months Ended  Year        Year       Year       Year       Year
                                                            9/30/09           Ended       Ended      Ended      Ended      Ended
                                                            (unaudited)       3/31/09     3/31/08    3/31/07    3/31/06    3/31/05
----------------------------------------------------------------------------------------------------------------------------------
                                                                                                         
Per Common Share Operating Performance
Net asset value, beginning of period                        $ 9.23            $ 13.54     $15.91     $15.04     $14.64     $14.51
----------------------------------------------------------------------------------------------------------------------------------
Increase (decrease) from investment operations:(a)
 Net investment income                                      $ 0.61            $  1.22     $ 1.29     $ 1.16     $ 1.17     $ 1.26
 Net realized and unrealized gain (loss) on investments
  and interest rate swaps                                     2.75              (4.43)     (2.51)      0.80       0.39       0.18
 Dividends and distributions to preferred shareowners from:
  Net investment income                                      (0.02)             (0.20)     (0.26)     (0.23)     (0.17)     (0.09)
  Net realized gains                                            --                 --         --         --         --      (0.01)
----------------------------------------------------------------------------------------------------------------------------------
 Net increase (decrease) from investment operations         $ 3.34            $ (3.41)    $(1.48)    $ 1.73     $ 1.39     $ 1.34
Dividends and distributions to common shareowners from:
 Net investment income                                       (0.46)             (0.90)     (0.89)     (0.86)     (0.99)     (1.13)
 Net realized gains                                             --                 --         --         --         --      (0.09)
Capital charge with respect to issuance of common shares:       --                 --         --         --         --       0.01
----------------------------------------------------------------------------------------------------------------------------------
Net increase (decrease) in net asset value                  $ 2.88            $ (4.31)    $(2.37)    $ 0.87     $ 0.40     $ 0.13
----------------------------------------------------------------------------------------------------------------------------------
Net asset value, end of period(b)                           $12.11            $  9.23     $13.54     $15.91     $15.04     $14.64
==================================================================================================================================
Market value, end of period(b)                              $12.22            $  9.04     $13.74     $15.61     $14.99     $14.37
----------------------------------------------------------------------------------------------------------------------------------
Total return at market value(c)                              41.15%            (28.40)%    (6.51)%    10.21%     11.55%      4.07%
Ratios to average net assets of common shareowners
 Net expenses(d)                                              1.47%(e)           1.38%      1.13%      1.16%      1.16%      1.18%
 Net investment income before preferred share dividends      11.88%(e)          10.70%      8.27%      7.47%      7.88%      8.94%
 Preferred share dividends                                    0.44%(e)           1.76%      1.64%      1.47%      1.17%      0.64%
 Net investment income available to common shareowners       11.44%(e)           8.94%      6.63%      6.00%      6.71%      8.30%
Portfolio turnover                                               3%(e)             24%        12%        17%        19%        39%


The accompanying notes are an integral part of these financial statements.

24   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09




------------------------------------------------------------------------------------------------------------------------------------
                                                               Six Months Ended  Year       Year       Year      Year      Year
                                                                9/30/09          Ended      Ended      Ended     Ended     Ended
                                                                (unaudited)      3/31/09    3/31/08    3/31/07   3/31/06   3/31/05
------------------------------------------------------------------------------------------------------------------------------------
                                                                                                         
Net assets of common shareowners, end of period (in thousands)  $277,654         $211,147   $308,500   $361,888  $342,012  $332,374
Preferred shares outstanding (in thousands)                     $150,000         $150,000   $150,000   $150,000  $150,000  $150,000
Asset coverage per preferred share, end of period               $ 71,277         $ 60,192   $ 76,427   $ 85,328  $ 82,011  $ 80,396
Average market value per preferred share(f)                     $ 25,000         $ 25,000   $ 25,000   $ 25,000  $ 25,000  $ 25,000
Liquidation value, including dividends payable, per
  preferred share                                               $ 25,001         $ 25,001   $ 25,010   $ 25,013  $ 25,009  $ 25,000
Ratios to average net assets of common shareowners before
  waivers and reimbursement of expenses
  Net expenses(d)                                                   1.47%(e)         1.38%      1.13%      1.18%     1.16%     1.19%
  Net investment income before preferred share dividends           11.88%(e)        10.70%      8.27%      7.45%     7.88%     8.93%
  Preferred share dividends                                         0.44%(e)         1.76%      1.64%      1.47%     1.17%     0.64%
  Net investment income available to common shareowners            11.44%(e)         8.94%      6.63%      5.98%     6.71%     8.29%
====================================================================================================================================


(a)  The per common share data presented above is based upon the average common
     shares outstanding for the periods presented.
(b)  Net asset value and market value are published in Barron's on Saturday, The
     Wall Street Journal on Monday and The New York Times on Monday and
     Saturday.
(c)  Total investment return is calculated assuming a purchase of common shares
     at the current market value on the first day and a sale at the current
     market value on the last day of the periods reported. Dividends and
     distributions, if any, are assumed for purposes of this calculation to be
     reinvested at prices obtained under the Trust's dividend reinvestment plan.
     Total investment return does not reflect brokerage commissions. Total
     investment returns covering less than a full period are not annualized.
     Past performance is not a guarantee of future results.
(d)  Expense ratios do not reflect the effect of dividend payments to preferred
     shareowners.
(e)  Annualized.
(f)  Market value is redemption value without an active market.

The information above represents the operating performance data for a common
share outstanding, total investment return, ratios to average net assets and
other supplemental data for the periods indicated. This information has been
determined based upon financial information provided in the financial
statements and market value data for the Trust's common shares.

The accompanying notes are an integral part of these financial statements.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   25


Notes to Financial Statements | 9/30/09 (unaudited)

1. Organization and Significant Accounting Policies

Pioneer Municipal High Income Advantage Trust (the Trust) was organized as a
Delaware statutory trust on August 6, 2003. Prior to commencing operations on
October 20, 2003, the Trust had no operations other than matters relating to
its organization and registration as a diversified, closed-end management
investment company under the Investment Company Act of 1940, as amended. The
investment objective of the Trust is to seek a high level of current income
exempt from regular federal income tax, and the Trust may seek capital
appreciation to the extent that it is consistent with its primary investment
objective.

The Trust may invest in both investment and below investment grade (high-yield)
municipal securities with a broad range of maturities and credit ratings. Debt
securities rated below investment grade are commonly referred to as "junk
bonds" and are considered speculative. These securities involve greater risk of
loss, are subject to greater price volatility, and are less liquid, especially
during periods of economic uncertainty or change, than higher rated debt
securities.

Information regarding the Trust's principal risks is contained in the Trust's
original offering prospectus, with additional information included in the
Trust's shareowner reports from time to time. Please refer to those documents
when considering the Trust's risks. At times, the Trust's investments may
represent industries or industry sectors that are interrelated or have common
risks, making it more susceptible to any economic, political, or regulatory
developments or other risks affecting those industries and sectors.

The Trust's financial statements have been prepared in conformity with U.S.
generally accepted accounting principles that require the management of the
Trust to, among other things, make estimates and assumptions that affect the
reported amounts of assets and liabilities, and the reported amounts of income,
expenses and gains and losses on investments during the reporting year. Actual
results could differ from those estimates.

The following is a summary of significant accounting policies followed by the
Trust in the preparation of its financial statements, which are consistent with
those policies generally accepted in the investment company industry:

A. Security Valuation

   Security transactions are recorded as of trade date. Securities are valued at
   prices supplied by independent pricing services, which consider such factors
   as Treasury spreads, yields, maturities and ratings. Valuations may be

26   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


   supplemented by values obtained from dealers and other sources, as required.
   The values of interest rate swaps are determined by obtaining dealer
   quotations. Securities for which there are no other readily available
   valuation methods are valued using fair value methods pursuant to procedures
   adopted by the Board of Trustees (board determined). The Trust may also use
   fair value methods to value a security including a non-U.S. security, when
   the closing market price on the principal exchange where the security is
   traded no longer reflects the value of the security. At September 30, 2009,
   there were no securities values that were board determined. Temporary cash
   investments are valued at amortized cost which approximates market value.

   Dividend income is recorded on the ex-dividend date, except that certain
   dividends from foreign securities where the ex-dividend date may have passed
   are recorded as soon as the Trust becomes aware of the ex-dividend data in
   the exercise of reasonable diligence. Discount and premium on debt securities
   are accreted or amortized, respectively, daily on an effective yield to
   maturity basis and are included in interest income. Interest income,
   including interest-bearing cash accounts, is recorded on an accrual basis.

   Gains and losses on sales of investments are calculated on the identified
   cost method for both financial reporting and federal income tax purposes.

B. Federal Income Taxes

   It is the Trust's policy to comply with the requirements of the Internal
   Revenue Code applicable to regulated investment companies and to distribute
   all of its taxable income and net realized capital gains, if any, to its
   shareowners. Therefore, no federal income tax provision is required. Tax
   years for the prior three fiscal years remain subject to examination by tax
   authorities.

   The amounts and characterizations of distributions to shareowners for
   financial reporting purposes are determined in accordance with federal income
   tax rules. Therefore, the sources of the Trust's distributions may be shown
   in the accompanying financial statements as either from or in excess of net
   investment income or net realized gain (loss) on investments transactions, or
   as from paid-in capital, depending on the type of book/tax differences that
   may exist.

   The tax character of distributions paid to common and preferred shareowners
   will be determined at the end of the fiscal year. Distributions during the
   year ended March 31, 2009 were as follows:



   -----------------------------------------------------------------------------
                                                                           2009
   -----------------------------------------------------------------------------
                                                                 
   Distributions paid from:
   Tax exempt income                                                $24,983,891
   Ordinary income                                                      142,565
   -----------------------------------------------------------------------------
     Total                                                          $25,126,456
   =============================================================================


Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   27


   The following shows the components of distributable earnings (losses) on a
   federal income tax basis at March 31, 2009:



   -----------------------------------------------------------------------------
                                                                           2009
   -----------------------------------------------------------------------------
                                                               
   Distributable earnings:
   Undistributed tax-exempt income                                   $4,256,946
   Undistributed ordinary income                                         29,674
   Capital loss carryforward                                        (32,280,990)
   Post-October-loss deferred                                       (16,483,090)
   Dividends payable                                                     (5,409)
   Unrealized depreciation                                          (69,800,759)
   -----------------------------------------------------------------------------
     Total                                                        $(114,283,628)
   =============================================================================


   The difference between book-basis and tax-basis unrealized depreciation is
   primarily attributable to the difference between book and tax amortization
   methods for premiums and discounts on fixed income securities, the difference
   between book and tax accounting for swap agreements, book/tax difference in
   accrual of income on securities in default, and other temporary differences.

C. Automatic Dividend Reinvestment Plan

   All common shareowners automatically participate in the Automatic Dividend
   Reinvestment Plan (the Plan), under which participants receive all dividends
   and capital gain distributions (collectively, dividends) in full and
   fractional common shares of the Trust in lieu of cash. Shareowners may elect
   not to participate in the Plan. Shareowners not participating in the Plan
   receive all dividends and capital gain distributions in cash. Participation
   in the Plan is completely voluntary and may be terminated or resumed at any
   time without penalty by notifying American Stock Transfer & Trust Company,
   the agent for shareowners in administering the Plan (the Plan Agent), in
   writing prior to any dividend record date; otherwise such termination or
   resumption will be effective with respect to any subsequently declared
   dividend or other distribution.

   Whenever the Trust declares a dividend on common shares payable in cash,
   participants in the Plan will receive the equivalent in common shares
   acquired by the Plan Agent either (i) through receipt of additional unissued
   but authorized common shares from the Trust or (ii) by purchase of
   outstanding common shares on the New York Stock Exchange or elsewhere. If, on
   the payment date for any dividend, the net asset value per common share is
   equal to or less than the market price per share plus estimated brokerage
   trading fees (market premium), the Plan Agent will invest the dividend amount
   in newly issued common shares. The number of newly issued common shares to be
   credited to each account will be determined by dividing the dollar amount of
   the dividend by the net asset value per common share on the date the shares
   are issued, provided that the maximum discount from

28   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


   the then current market price per share on the date of issuance does not
   exceed 5%. If, on the payment date for any dividend, the net asset value per
   common share is greater than the market value (market discount), the Plan
   Agent will invest the dividend amount in common shares acquired in
   open-market purchases. There are no brokerage charges with respect to newly
   issued common shares. However, each participant will pay a pro rata share of
   brokerage trading fees incurred with respect to the Plan Agent's open-market
   purchases. Participating in the Plan does not relieve shareowners from any
   federal, state or local taxes which may be due on dividends paid in any
   taxable year. Shareowners holding Plan shares in a brokerage account may not
   be able to transfer the shares to another broker and continue to participate
   in the Plan.

2. Management Agreement

Pioneer Investment Management, Inc. (PIM), a wholly owned indirect subsidiary
of UniCredit S.p.A. (UniCredit), manages the Trust's portfolio. Management fees
payable under the Trust's Advisory Agreement with PIM are calculated daily at
the annual rate of 0.60% of the Trust's average daily managed assets. "Managed
assets" is the average daily value of the Trust's total assets (including any
asset attributable to any leverage that may be outstanding) minus the sum of
accrued liabilities (other than debt representing financial leverage). For the
six months ended September 30, 2009, the net management fee was equivalent to
0.60% of the Trust's average daily managed assets, which was equivalent to
0.98% of the Trust's average daily net assets attributable to the common
shareowners.

In addition, under PIM's management and administration agreements, certain
other services and costs are paid by PIM and reimbursed by the Trust. At
September 30, 2009, $212,519 was payable to PIM related to management costs,
administrative cost and certain other services and is included in "Due to
affiliates" on the Statement of Assets and Liabilities.

PIM has retained Princeton Administrators, LLC (Princeton) to provide certain
administrative and accounting services to the Trust on its behalf. The Trust
pays Princeton a monthly fee equal to 0.07% of the Trust's average daily
managed assets up to $500 million and 0.03% for average daily managed assets in
excess of $500 million, subject to a minimum monthly fee of $10,000.

3. Transfer Agents

Pioneer Investment Management Shareholder Services, Inc. (PIMSS), a wholly
owned indirect subsidiary of UniCredit, through a sub-transfer agency agreement
with American Stock Transfer & Trust Company provides substantially all
transfer agent and shareowner services related to the Trust's common shares at
negotiated rates. Deutsche Bank Trust Company Americas (Deutsche Bank) is the
transfer agent, registrar, dividend paying agent and auction agent with

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   29


respect to the Trust's Auction Preferred Shares (APS). The Trust pays Deutsche
Bank an annual fee, as is agreed to from time to time by the Trust and Deutsche
Bank, for providing such services.

4. Interest Rate Swaps

The Trust may enter into interest rate swap transactions to attempt to protect
itself from increasing dividend or interest expense on its leverage resulting
from increasing short-term interest rates. The cost of leverage may rise with
an increase in interest rates, generally having the effect of lower yields and
potentially lower dividends to common shareowners. Interest rate swaps can be
used to "lock in" the cost of leverage and reduce the negative impact that
rising short-term interest rates would have on the Trust's leveraging costs.

An interest rate swap is an agreement between two parties, which involves
exchanging floating rate and fixed rate interest payments for a specified
period of time. Interest rate swaps involve the accrual of the net interest
payments between the parties on a daily basis, with the net amount recorded
within the unrealized appreciation/depreciation of interest rate swaps on the
Statement of Assets and Liabilities. Once the interim payments are settled in
cash, at the pre-determined dates specified in the agreement, the net amount is
recorded as realized gain or loss from interest rate swaps on the Statement of
Operations. During the term of the swap, changes in the value of the swap are
recognized as unrealized gains and losses by "marking-to-market" the value of
the swap based on values obtained from dealer quotations. When the swap is
terminated, the Trust will record a realized gain or loss equal to the
difference, if any, between the proceeds from (or cost of) closing the contract
and the cost basis of the contract. The Trust is exposed to credit risk in the
event of non-performance by the other party to the interest rate swap. Risk may
also arise with regard to market movements in the value of the swap arrangement
that do not exactly offset the changes in the related dividend requirement or
interest expense on the Trust's leverage.

There were no interest rate swap contracts outstanding at September 30, 2009.

5. Trust Shares

There are an unlimited number of common shares of beneficial interest
authorized.

Transactions in common shares of beneficial interest for the six months ended
September 30, 2009 and the year ended March 31, 2009 were as follows:



--------------------------------------------------------------------------------
                                                       9/2009           3/2009
--------------------------------------------------------------------------------
                                                              
Shares outstanding at beginning of period          22,879,496       22,786,930
Reinvestment of distributions                          53,311           92,566
--------------------------------------------------------------------------------
Shares outstanding at end of period                22,932,807       22,879,496
================================================================================


30   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


The Trust may classify or reclassify any unissued common shares of beneficial
interest into one or more series of preferred shares of beneficial interest. As
of September 30, 2009, there were 6,000 APS as follows: Series A -- 3,000 and
Series B -- 3,000.

Dividends on Series A and Series B are cumulative at a rate, which is reset
every seven days based on the results of an auction. An auction fails if there
are more APS offered for sale than there are buyers. When an auction fails, the
dividend rate for the period will be the maximum rate on the auction dates
described in the prospectus for the APS. Preferred shareowners will not be able
to sell their APS at an auction if the auction fails. Since February 2008, the
Trust's auctions related to the APS have failed. The maximum rate for the 7-Day
Series is 125% of the 7 day commercial paper rate or adjusted Kenny rate.
Dividend rates ranged from 0.485% to 1.08% during the six months ended
September 30, 2009.

The Trust may not declare dividends or make other distributions on its common
shares or purchase any such shares if, at the time of the declaration,
distribution or purchase, the Trust does not comply with the asset coverage
ratios described in the prospectus for the APS.

The APS are redeemable at the option of the Trust, in whole or in part, on any
dividend payment date at $25,000 per share plus any accumulated or unpaid
dividends, whether or not declared. The APS are also subject to mandatory
redemption at $25,000 per share plus any accumulated or unpaid dividends,
whether or not declared, if certain requirements relating to the composition of
the assets and liabilities of the Trust as set forth in the Statement of
Preferences are not satisfied.

The holders of APS have voting rights equal to the holders of the Trust's
common shares (one vote per share) and will vote together with holders of the
common shares as a single class. However, holders of APS are also entitled to
elect two of the Trust's Trustees. In addition, the Investment Company Act of
1940, as amended, requires that along with approval by shareowners that might
otherwise be required, the approval of the holders of a majority of any
outstanding preferred shares, voting separately as a class, would be required
to (a) adopt any plan of reorganization that would adversely affect the
preferred shares and (b) take any action requiring a vote of security holders,
including, among other things, changes in the Trust's subclassification as a
closed-end management investment company or changes in its fundamental
investment restrictions.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   31


6. Additional Disclosures about Derivative Instruments and Hedging Activities:

The effect of derivative instruments on the Statement of Operations for the six
months ended September 30, 2009 was as follows:



---------------------------------------------------------------------------------------------------------------
    Derivatives Not                                                                                 Change in
   Accounted for as                                                        Realized Gain or     Unrealized Gain
       Hedging                                                                (Loss) on          or (Loss) on
     Instruments                    Location of Gain or (Loss)               Derivatives          Derivatives
   Under Statement                 On Derivatives Recognized                Recognized in        Recognized in
         133                               in Income                            Income              Income
---------------------------------------------------------------------------------------------------------------
                                                                                          
 Interest Rate Swap       Net realized (loss) from interest rate swaps       $(135,950)            $131,406


7. Subsequent Events

Subsequent to September 30, 2009, the Board of Trustees of the Trust declared a
dividend from undistributed net investment income of $0.080 per common share
payable October 30, 2009, to common shareowners of record on October 15, 2009.

Subsequent to September 30, 2009, dividends declared and paid on preferred
shares totaled $63,810 in aggregate for the two outstanding preferred share
series through November 9, 2009.

In preparing these financial statements, PIM has evaluated the impact of all
events and transactions for potential recognition or disclosure through
November 23, 2009, and has determined that there were no events requiring
recognition or disclosure in the financial statements.

32   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


ADDITIONAL INFORMATION (unaudited)

During the period, there have been no material changes in the Trust's
investment objective or fundamental policies that have not been approved by the
shareowners. There have been no changes in the Trust's charter or By-Laws that
would delay or prevent a change in control of the Trust which has not been
approved by the shareowners. There have been no changes in the principal risk
factors associated with investment in the Trust. Day-to-day management of the
Trust's portfolio is the responsibility of David Eurkus. Mr. Eurkus is
supported by the fixed income team. Members of this team manage other Pioneer
funds investing primarily in fixed income securities. The portfolio manager and
the team also may draw upon the research and investment management expertise of
Pioneer's affiliate, Pioneer Investment Management Limited. Mr. Eurkus joined
Pioneer as a senior vice president in January 2000 and has been an investment
professional since 1969.

Notice is hereby given in accordance with Section 23(c) of the Investment
Company Act of 1940 that the Trust may purchase, from time to time, its common
shares in the open market.

CEO CERTIFICATION DISCLOSURE (unaudited)

The Trust's Chief Executive Officer has submitted to the New York Stock
Exchange the annual CEO certification as required by Section 303A.12(a) of the
NYSE Listed Company Manual. In addition, the Trust has filed with the
Securities and Exchange Commission the certification of its Chief Executive
Officer and Chief Financial Officer required by Section 302 of the Sarbanes-
Oxley Act.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   33


Results of Shareholder Meeting (unaudited)

At the annual meeting of shareowners held on September 22, 2009 shareowners of
Pioneer Municipal High Income Advantage Trust were asked to consider the
proposals described below. A report of the total votes cast by the Trust's
shareholders follows:

Proposal 1 -- To elect Class III Trustees.



-------------------------------------------------------------------------------
 Nominee                                       For                    Withheld
-------------------------------------------------------------------------------
                                                                
 Mary K. Bush                                  13,238,097             643,607
 Thomas J. Perna                               13,293,348             588,356
 Marguerite A. Piret+                               4,605                 109


------------------
+ Elected by Preferred Shares only

Proposal 2 -- To approve an Amended and Restated Management Agreement with
Pioneer Investment Management, Inc.



-------------------------------------------------------------------------------
                                                                  Broker
 For                    Against               Abstain             Non-Votes
-------------------------------------------------------------------------------
                                                         
 9,532,084             305,035                318,467             3,726,118


34   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


Trustees, Officers and Service Providers

Trustees                                      Officers
John F. Cogan, Jr., Chairman                  John F. Cogan, Jr., President
David R. Bock                                 Daniel K. Kingsbury, Executive
Mary K. Bush                                    Vice President
Benjamin M. Friedman                          Mark E. Bradley, Treasurer
Margaret B.W. Graham                          Dorothy E. Bourassa, Secretary
Daniel K. Kingsbury
Thomas J. Perna
Marguerite A. Piret
Stephen K. West

Investment Adviser
Pioneer Investment Management, Inc.

Custodian
Brown Brothers Harriman & Co.

Legal Counsel
Bingham McCutchen LLP

Transfer Agent
Pioneer Investment Management Shareholder Services, Inc.

Shareowner Services and Sub-Transfer Agent
American Stock Transfer & Trust Company

Preferred Share Auction/Transfer Agent and Registrar
Deutsche Bank Trust Company Americas

Sub-Administrator
Princeton Administrators, LLC

Proxy Voting Policies and Procedures of the Trust are available without charge,
upon request, by calling our toll free number (1-800-225-6292). Information
regarding how the Trust voted proxies relating to portfolio securities during
the most recent 12-month period ended June 30 is publicly available to
shareowners at pioneerinvestments.com. This information is also available on
the Securities and Exchange Commission's web site at http://www.sec.gov.

Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09   35





                           This page for your notes.




36   Pioneer Municipal High Income Advantage Trust | Semiannual Report | 9/30/09


How to Contact Pioneer

We are pleased to offer a variety of convenient ways for you to contact us for
assistance or information.

You can call American Stock Transfer & Trust Company (AST) for:
--------------------------------------------------------------------------------
Account Information                             1-800-710-0935

Or write to AST:
--------------------------------------------------------------------------------

For                                             Write to

General inquiries, lost dividend checks,        American Stock
change of address, lost stock certificates,     Transfer & Trust
stock transfer                                  Operations Center
                                                6201 15th Ave.
                                                Brooklyn, NY 11219

Dividend reinvestment plan (DRIP)               American Stock
                                                Transfer & Trust
                                                Wall Street Station
                                                P.O. Box 922
                                                New York, NY 10269-0560

Website                                         www.amstock.com

For additional information, please contact your investment advisor or visit our
web site www.pioneerinvestments.com.

The Trust files a complete statement of investments with the Securities and
Exchange Commission for the first and third quarters for each fiscal year on
Form N-Q. Shareowners may view the filed Form N-Q by visiting the Commission's
web site at http://www.sec.gov. The filed form may also be viewed and copied at
the Commission's Public Reference Room in Washington, DC. Information regarding
the operations of the Public Reference Room may be obtained by calling
1-800-SEC-0330.

The Trust's Chief Executive Officer is required by the New York Stock
Exchange's Listing Standards to file annually with the Exchange a certification
that he is not aware of any violation by the Trust of the Exchange's Corporate
Governance Standards applicable to the Trust. The Trust has filed such
certification.


ITEM 2. CODE OF ETHICS.

(a) Disclose whether, as of the end of the period covered by the report, the
registrant has adopted a code of ethics that applies to the registrant's
principal executive officer, principal financial officer, principal accounting
officer or controller, or persons performing similar functions, regardless of
whether these individuals are employed by the registrant or a third party.  If
the registrant has not adopted such a code of ethics, explain why it has not
done so.

The registrant has adopted, as of the end of the period covered by this report,
a code of ethics that applies to the registrant's principal executive officer,
principal financial officer, principal accounting officer and controller.

(b) For purposes of this Item, the term "code of ethics" means written standards
that are reasonably designed to deter wrongdoing and to promote:

        (1) Honest and ethical conduct, including the ethical handling of actual
        or apparent conflicts of interest between personal and professional
        relationships;

        (2) Full, fair, accurate, timely, and understandable disclosure in
        reports and documents that a registrant files with, or submits to, the
        Commission and in other public communications made by the registrant;

        (3) Compliance with applicable governmental laws, rules, and
        regulations;

        (4) The prompt internal reporting of violations of the code to an
        appropriate person or persons identified in the code; and

        (5) Accountability for adherence to the code.

(c) The registrant must briefly describe the nature of any amendment, during the
period covered by the report, to a provision of its code of ethics that applies
to the registrant's principal executive officer, principal financial officer,
principal accounting officer or controller, or persons performing similar
functions, regardless of whether these individuals are employed by the
registrant or a third party, and that relates to any element of the code of
ethics definition enumerated in paragraph (b) of this Item. The registrant must
file a copy of any such amendment as an exhibit pursuant to Item 10(a), unless
the registrant has elected to satisfy paragraph (f) of this Item by posting its
code of ethics on its website pursuant to paragraph (f)(2) of this Item, or by
undertaking to provide its code of ethics to any person without charge, upon
request, pursuant to paragraph (f)(3) of this Item.

The registrant has made no amendments to the code of ethics during the period
covered by this report.

(d) If the registrant has, during the period covered by the report, granted a
waiver, including an implicit waiver, from a provision of the code of ethics to
the registrant's principal executive officer, principal financial officer,
principal accounting officer or controller, or persons performing similar
functions, regardless of whether these individuals are employed by the
registrant or a third party, that relates to one or more of the items set forth
in paragraph (b) of this Item, the registrant must briefly describe the nature
of the waiver, the name of the person to whom the waiver was granted, and the
date of the waiver.

Not applicable.

(e) If the registrant intends to satisfy the disclosure requirement under
paragraph (c) or (d) of this Item regarding an amendment to, or a waiver from,
a provision of its code of ethics that applies to the registrant's principal
executive officer, principal financial officer, principal accounting officer or
controller, or persons performing similar functions and that relates to any
element of the code of ethics definition enumerated in paragraph (b) of this
Item by posting such information on its Internet website, disclose the
registrant's Internet address and such intention.

Not applicable.

(f) The registrant must:

        (1) File with the Commission, pursuant to Item 10(a), a copy of its code
        of ethics that applies to the registrant's principal executive officer,
        principal financial officer, principal accounting officer or controller,
        or persons performing similar functions, as an exhibit to its annual
        report on this Form N-CSR;

        (2) Post the text of such code of ethics on its Internet website and
        disclose, in its most recent report on this Form N-CSR, its Internet
        address and the fact that it has posted such code of ethics on its
        Internet website; or

        (3) Undertake in its most recent report on this Form N-CSR to provide to
        any person without charge, upon request, a copy of such code of ethics
        and explain the manner in which such request may be made.
	See Item 10(2)

ITEM 3. AUDIT COMMITTEE FINANCIAL EXPERT.

(a) (1)  Disclose that the registrant's board of trustees has determined that
         the registrant either:

    (i)  Has at least one audit committee financial expert serving on its audit
         committee; or

    (ii) Does not have an audit committee financial expert serving on its audit
         committee.

The registrant's Board of Trustees has determined that the registrant has at
least one audit committee financial expert.

    (2) If the registrant provides the disclosure required by paragraph
(a)(1)(i) of this Item, it must disclose the name of the audit committee
financial expert and whether that person is "independent." In order to be
considered "independent" for purposes of this Item, a member of an audit
committee may not, other than in his or her capacity as a member of the audit
committee, the board of trustees, or any other board committee:

    (i)  Accept directly or indirectly any consulting, advisory, or other
         compensatory fee from the issuer; or

    (ii) Be an "interested person" of the investment company as defined in
         Section 2(a)(19) of the Act (15 U.S.C. 80a-2(a)(19)).

Ms. Marguerite A. Piret, an independent trustee, is such an audit committee
financial expert.

    (3) If the registrant provides the disclosure required by paragraph (a)(1)
(ii) of this Item, it must explain why it does not have an audit committee
financial expert.

Not applicable.


ITEM 4. PRINCIPAL ACCOUNTANT FEES AND SERVICES.

(a) Disclose, under the caption AUDIT FEES, the aggregate fees billed for each
of the last two fiscal years for professional services rendered by the principal
accountant for the audit of the registrant's annual financial statements or
services that are normally provided by the accountant in connection with
statutory and regulatory filings or engagements for those fiscal years.

N/A

(b) Disclose, under the caption AUDIT-RELATED FEES, the aggregate fees billed in
each of the last two fiscal years for assurance and related services by the
principal accountant that are reasonably related to the performance of the audit
of the registrant's financial statements and are not reported under
paragraph (a) of this Item. Registrants shall describe the nature of the
services comprising the fees disclosed under this category.


N/A

(c) Disclose, under the caption TAX FEES, the aggregate fees billed in each of
the last two fiscal years for professional services rendered by the principal
accountant for tax compliance, tax advice, and tax planning. Registrants shall
describe the nature of the services comprising the fees disclosed under this
category.


N/A

(d) Disclose, under the caption ALL OTHER FEES, the aggregate fees billed in
each of the last two fiscal years for products and services provided by the
principal accountant, other than the services reported in paragraphs (a) through
(c) of this Item. Registrants shall describe the nature of the services
comprising the fees disclosed under this category.

N/A

(e) (1) Disclose the audit committee's pre-approval policies and procedures
described in paragraph (c)(7) of Rule 2-01 of Regulation S-X.

 PIONEER FUNDS
            APPROVAL OF AUDIT, AUDIT-RELATED, TAX AND OTHER SERVICES
                       PROVIDED BY THE INDEPENDENT AUDITOR

                  SECTION I - POLICY PURPOSE AND APPLICABILITY

The Pioneer Funds recognize the importance of maintaining the independence of
their outside auditors. Maintaining independence is a shared responsibility
involving Pioneer Investment Management, Inc ("PIM"), the audit committee and
the independent auditors.

The Funds recognize that a Fund's independent auditors: 1) possess knowledge of
the Funds, 2) are able to incorporate certain services into the scope of the
audit, thereby avoiding redundant work, cost and disruption of Fund personnel
and processes, and 3) have expertise that has value to the Funds. As a result,
there are situations where it is desirable to use the Fund's independent
auditors for services in addition to the annual audit and where the potential
for conflicts of interests are minimal. Consequently, this policy, which is
intended to comply with Rule 210.2-01(C)(7), sets forth guidelines and
procedures to be followed by the Funds when retaining the independent audit firm
to perform audit, audit-related tax and other services under those
circumstances, while also maintaining independence.

Approval of a service in accordance with this policy for a Fund shall also
constitute approval for any other Fund whose pre-approval is required pursuant
to Rule 210.2-01(c)(7)(ii).

In addition to the procedures set forth in this policy, any non-audit services
that may be provided consistently with Rule 210.2-01 may be approved by the
Audit Committee itself and any pre-approval that may be waived in accordance
with Rule 210.2-01(c)(7)(i)(C) is hereby waived.

Selection of a Fund's independent auditors and their compensation shall be
determined by the Audit Committee and shall not be subject to this policy.



                               SECTION II - POLICY

---------------- -------------------------------- -------------------------------------------------
SERVICE           SERVICE CATEGORY DESCRIPTION      SPECIFIC PRE-APPROVED SERVICE SUBCATEGORIES
CATEGORY
---------------- -------------------------------- -------------------------------------------------
                                            
I.  AUDIT        Services that are directly       o Accounting research assistance
SERVICES         related to performing the        o SEC consultation, registration
                 independent audit of the Funds     statements, and reporting
                                                  o Tax accrual related matters
                                                  o Implementation of new accounting
                                                    standards
                                                  o Compliance letters (e.g. rating agency
                                                    letters)
                                                  o Regulatory reviews and assistance
                                                    regarding financial matters
                                                  o Semi-annual reviews (if requested)
                                                  o Comfort letters for closed end
                                                    offerings
---------------- -------------------------------- -------------------------------------------------
II.              Services which are not           o AICPA attest and agreed-upon procedures
AUDIT-RELATED    prohibited under Rule            o Technology control assessments
SERVICES         210.2-01(C)(4) (the "Rule")      o Financial reporting control assessments
                 and are related extensions of    o Enterprise security architecture
                 the audit services support the     assessment
                 audit, or use the
                 knowledge/expertise gained
                 from the audit procedures as a
                 foundation to complete the
                 project.  In most cases, if
                 the Audit-Related Services are
                 not performed by the Audit
                 firm, the scope of the Audit
                 Services would likely
                 increase.  The Services are
                 typically well-defined and
                 governed by accounting
                 professional standards (AICPA,
                 SEC, etc.)
---------------- -------------------------------- -------------------------------------------------

 ------------------------------------- ------------------------------------
                                    
   AUDIT COMMITTEE APPROVAL POLICY               AUDIT COMMITTEE
                                                REPORTING POLICY
 ------------------------------------- ------------------------------------
                                    
 o "One-time" pre-approval             o A summary of all such
   for the audit period for all          services and related fees
   pre-approved specific service         reported at each regularly
   subcategories.  Approval of the       scheduled Audit Committee
   independent auditors as               meeting.
   auditors for a Fund shall
   constitute pre approval for
   these services.
 ------------------------------------- ------------------------------------
 o "One-time" pre-approval             o A summary of all such
   for the fund fiscal year within       services and related fees
   a specified dollar limit              (including comparison to
   for all pre-approved                  specified dollar limits)
   specific service subcategories        reported quarterly.

 o Specific approval is
   needed to exceed the
   pre-approved dollar limit for
   these services (see general
   Audit Committee approval policy
   below for details on obtaining
   specific approvals)

 o Specific approval is
   needed to use the Fund's
   auditors for Audit-Related
   Services not denoted as
   "pre-approved", or
   to add a specific service
   subcategory as "pre-approved"
 ------------------------------------- ------------------------------------




                     SECTION III - POLICY DETAIL, CONTINUED

----------------------- --------------------------- -----------------------------------------------
   SERVICE CATEGORY          SERVICE CATEGORY        SPECIFIC PRE-APPROVED SERVICE SUBCATEGORIES
                               DESCRIPTION
----------------------- --------------------------- -----------------------------------------------
                                              
III. TAX SERVICES       Services which are not      o Tax planning and support
                        prohibited by the Rule,     o Tax controversy assistance
                        if an officer of the Fund   o Tax compliance, tax returns, excise
                        determines that using the     tax returns and support
                        Fund's auditor to provide   o Tax opinions
                        these services creates
                        significant synergy in
                        the form of efficiency,
                        minimized disruption, or
                        the ability to maintain a
                        desired level of
                        confidentiality.
----------------------- --------------------------- -----------------------------------------------

------------------------------------- -------------------------
  AUDIT COMMITTEE APPROVAL POLICY         AUDIT COMMITTEE
                                          REPORTING POLICY
------------------------------------- -------------------------
------------------------------------- -------------------------
o "One-time" pre-approval             o A summary of
  for the fund fiscal  year             all such services and
  within a specified dollar limit       related fees
  				        (including comparison
  			                to specified dollar
  			                limits) reported
  			                quarterly.

o Specific approval is
  needed to exceed the
  pre-approved dollar limits for
  these services (see general
  Audit Committee approval policy
  below for details on obtaining
  specific approvals)

o Specific approval is
  needed to use the Fund's
  auditors for tax services not
  denoted as pre-approved, or to add a specific
  service subcategory as
  "pre-approved"
------------------------------------- -------------------------




                     SECTION III - POLICY DETAIL, CONTINUED

----------------------- --------------------------- -----------------------------------------------
   SERVICE CATEGORY          SERVICE CATEGORY        SPECIFIC PRE-APPROVED SERVICE SUBCATEGORIES
                               DESCRIPTION
----------------------- --------------------------- -----------------------------------------------
                                              
IV.  OTHER SERVICES     Services which are not      o Business Risk Management support
                        prohibited by the Rule,     o Other control and regulatory
A. SYNERGISTIC,         if an officer of the Fund     compliance projects
UNIQUE QUALIFICATIONS   determines that using the
                        Fund's auditor to provide
                        these services creates
                        significant synergy in
                        the form of efficiency,
                        minimized disruption,
                        the ability to maintain a
                        desired level of
                        confidentiality, or where
                        the Fund's auditors
                        posses unique or superior
                        qualifications to provide
                        these services, resulting
                        in superior value and
                        results for the Fund.
----------------------- --------------------------- -----------------------------------------------

--------------------------------------- ------------------------
    AUDIT COMMITTEE APPROVAL POLICY         AUDIT COMMITTEE
                                            REPORTING POLICY
------------------------------------- --------------------------
                                   
o "One-time" pre-approval             o A summary of
  for the fund fiscal year within       all such services and
  a specified dollar limit              related fees
  			               (including comparison
  			                to specified dollar
  				        limits) reported
                                        quarterly.
o Specific approval is
  needed to exceed the
  pre-approved dollar limits for
  these services (see general
  Audit Committee approval policy
  below for details on obtaining
  specific approvals)

o Specific approval is
  needed to use the Fund's
  auditors for "Synergistic" or
  "Unique Qualifications" Other
  Services not denoted as
  pre-approved to the left, or to
  add a specific service
  subcategory as "pre-approved"
------------------------------------- --------------------------




                     SECTION III - POLICY DETAIL, CONTINUED

----------------------- ------------------------- -----------------------------------------------
   SERVICE CATEGORY         SERVICE CATEGORY        SPECIFIC PROHIBITED SERVICE SUBCATEGORIES
                              DESCRIPTION
----------------------- ------------------------- -----------------------------------------------
                                            
PROHIBITED  SERVICES    Services which result     1. Bookkeeping or other services
                        in the auditors losing       related to the accounting records or
                        independence status          financial statements of the audit
                        under the Rule.              client*
                                                  2. Financial information systems design
                                                     and implementation*
                                                  3. Appraisal or valuation services,
                                                     fairness* opinions, or
                                                     contribution-in-kind reports
                                                  4. Actuarial services (i.e., setting
                                                     actuarial reserves versus actuarial
                                                     audit work)*
                                                  5. Internal audit outsourcing services*
                                                  6. Management functions or human
                                                     resources
                                                  7. Broker or dealer, investment
                                                     advisor, or investment banking services
                                                  8. Legal services and expert services
                                                     unrelated to the audit
                                                  9. Any other service that the Public
                                                     Company Accounting Oversight Board
                                                     determines, by regulation, is
                                                     impermissible
----------------------- ------------------------- -----------------------------------------------

------------------------------------------- ------------------------------
     AUDIT COMMITTEE APPROVAL POLICY               AUDIT COMMITTEE
                                                  REPORTING POLICY
------------------------------------------- ------------------------------
o These services are not to be              o A summary of all
  performed with the exception of the(*)      services and related
  services that may be permitted              fees reported at each
  if they would not be subject to audit       regularly scheduled
  procedures at the audit client (as          Audit Committee meeting
  defined in rule 2-01(f)(4)) level           will serve as continual
  the firm providing the service.             confirmation that has
  				              not provided any
                                              restricted services.
------------------------------------------- ------------------------------

--------------------------------------------------------------------------------
GENERAL AUDIT COMMITTEE APPROVAL POLICY:
o For all projects, the officers of the Funds and the Fund's auditors will each
  make an assessment to determine that any proposed projects will not impair
  independence.

o Potential services will be classified into the four non-restricted service
  categories and the "Approval of Audit, Audit-Related, Tax and Other
  Services" Policy above will be applied. Any services outside the specific
  pre-approved service subcategories set forth above must be specifically
  approved by the Audit Committee.

o At least quarterly, the Audit Committee shall review a report summarizing the
  services by service category, including fees, provided by the Audit firm as
  set forth in the above policy.

--------------------------------------------------------------------------------


    (2) Disclose the percentage of services described in each of paragraphs (b)
   through (d) of this Item that were approved by the audit committee pursuant
   to paragraph (c)(7)(i)(C) of Rule 2-01 of Regulation S-X.

N/A

(f) If greater than 50 percent, disclose the percentage of hours expended on the
principal accountant's engagement to audit the registrant's financial statements
for the most recent fiscal year that were attributed to work performed by
persons other than the principal accountant's full-time, permanent employees.

N/A

(g) Disclose the aggregate non-audit fees billed by the registrant's accountant
for services rendered to the registrant, and rendered to the registrant's
investment adviser (not including any sub-adviser whose role is primarily
portfolio management and is subcontracted with or overseen by another investment
adviser), and any entity controlling, controlled by, or under common control
with the adviser that provides ongoing services to the registrant for each of
the last two fiscal years of the registrant.


N/A

(h) Disclose whether the registrant's audit committee of the board of trustees
has considered whether the provision of non-audit services that were rendered to
the registrant's investment adviser (not including any subadviser whose role is
primarily portfolio management and is subcontracted with or overseen by another
investment adviser), and any entity controlling, controlled by, or under common
control with the investment adviser that provides ongoing services to the
registrant that were not pre-approved pursuant to paragraph (c)(7)(ii) of
Rule 2-01 of Regulation S-X is compatible with maintaining the principal
accountant's independence.

The Fund's audit committee of the Board of Trustees has
considered whether the provision of non-audit services that
were rendered to the Affiliates (as defined) that were not pre-
approved pursuant to paragraph (c)(7)(ii) of Rule 2-01 of
Regulation S-X is compatible with maintaining the principal
accountant's independence.

Item 5. Audit Committee of Listed Registrants

(a) If the registrant is a listed issuer as defined in Rule 10A-3
under the Exchange Act (17 CFR 240.10A-3), state whether
or not the registrant has a separately-designated standing
 audit committee established in accordance with Section
3(a)(58)(A) of the Exchange Act (15 U.S.C. 78c(a)(58)(A)).
If the registrant has such a committee, however designated,
identify each committee member. If the entire board of directors
is acting as the registrants audit committee as specified in
Section 3(a)(58)(B) of the Exchange Act (15 U.S.C. 78c(a)(58)(B)),
so state.

N/A

(b) If applicable, provide the disclosure required by Rule 10A-3(d)
under the Exchange Act (17 CFR 240.10A-3(d)) regarding an exemption
from the listing standards for audit committees.

N/A

Item 6. Schedule of Investments.

File Schedule I Investments in securities of unaffiliated issuers
as of the close of the reporting period as set forth in 210.12-
12 of Regulation S-X [17 CFR 210.12-12], unless the schedule is
included as part of the report to shareholders filed under Item
1 of this Form.

Included in Item 1


ITEM 7. DISCLOSURE OF PROXY VOTING POLICIES AND PROCEDURES FOR
CLOSED-END MANAGEMENT INVESTMENT COMPANIES.

A closed-end management investment company that is filing an annual report on
this Form N-CSR must, unless it invests exclusively in non-voting securities,
describe the policies and procedures that it uses to determine how to vote
proxies relating to portfolio securities, including the procedures that the
company uses when a vote presents a conflict between the interests of its
shareholders, on the one hand, and those of the company's investment adviser;
principal underwriter; or any affiliated person (as defined in Section 2(a)(3)
of the Investment Company Act of 1940 (15 U.S.C. 80a-2(a)(3)) and the rules
thereunder) of the company, its investment adviser, or its principal
underwriter, on the other. Include any policies and procedures of the company's
investment adviser, or any other third party, that the company uses, or that are
used on the company's behalf, to determine how to vote proxies relating to
portfolio securities.


Information not required in semi annual reports on form NCSR.



Item 8. Portfolio Managers of Closed-End Management Investment
        Companies.

(a) If the registrant is a closed-end management investment company that
is filing an annual report on this Form N-CSR,provide the following
information:
(1) State the name, title, and length of service of the person or persons
employed by or associated with the registrant or an investment adviser
of the registrant who are primarily responsible for the day-to-day management
of the registrants portfolio (Portfolio Manager). Also state each Portfolio
Managers business experience during the past 5 years.


Information not required in semi annual reports on form NCSR.


Item 9. Purchases of Equity Securities by Closed-End Management
Investment Company and Affiliated Purchasers.

(a) If the registrant is a closed-end management investment company,
in the following tabular format, provide the information specified in
paragraph (b) of this Item with respect to any purchase made by or on
behalf of the registrant or any affiliated purchaser, as defined in
Rule 10b-18(a)(3) under the Exchange Act (17 CFR 240.10b-18(a)(3)), of
shares or other units of any class of the registrants equity securities
that is registered by the registrant pursuant to Section 12 of the
Exchange Act (15 U.S.C. 781). Instruction to paragraph (a). Disclose
all purchases covered by this Item, including purchases that do not
satisfy the conditions of the safe harbor of Rule 10b-18 under the
Exchange Act (17 CFR 240.10b-18), made in the period covered by the
report. Provide disclosures covering repurchases made on a monthly basis.
For example, if the reporting period began on January 16 and ended on
July 15, the chart would show repurchases for the months from January 16
through February 15, February 16 through March 15, March 16 through
April 15, April 16 through May 15, May 16 through June 15, and June 16
through July 15.

During the period covered by this report, there were no purchases
made by or on behalf of the registrant or any affiliated purchaser
as defined in Rule 10b-18(a)(3) under the Securities Exchange Act
of 1934 (the Exchange Act), of shares of the registrants equity
securities that are registered by the registrant pursuant to
Section 12 of the Exchange Act.


Item 10. Submission of Matters to a Vote of Security Holders.

Describe any material changes to the procedures by which shareholders
may recommend nominees to the registrants board of directors, where
those changes were implemented after the registrant last provided
disclosure in response to the requirements of Item 7(d)(2)(ii)(G)
of Schedule 14A (17 CFR 240.14a-101), or this Item.


There have been no material changes to the procedures by which the
shareholders may recommend nominees to the registrants board of
directors since the registrant last provided disclosure in response
to the requirements of Item 7(d)(2)(ii)(G) of Schedule 14(A) in
its definitive proxy statement, or this Item.


ITEM 11. CONTROLS AND PROCEDURES.

(a) Disclose the conclusions of the registrant's principal executive officer or
officers and principal financial officer or officers, or persons performing
similar functions, about the effectiveness of the registrant's disclosure
controls and procedures (as defined in Rule 30a-2(c) under the Act (17 CFR
270.30a-2(c))) based on their evaluation of these controls and procedures as of
a date within 90 days of the filing date of the report that includes the
disclosure required by this paragraph.

The registrant's principal executive officer
and principal financial officer have
concluded that the registrant's disclosure
controls and procedures are effective based
on their evaluation of these controls and
procedures as of a date within 90 days of the
filing date of this report.


(b) Disclose whether or not there were significant changes in the registrant's
internal controls or in other factors that could significantly affect these
controls subsequent to the date of their evaluation, including any corrective
actions with regard to significant deficiencies and material weaknesses.

There were no significant changes in the
registrant's internal control over financial
reporting that occurred during the second
fiscal quarter of the period covered by this
report that have materially affected, or are
reasonably likely to materially affect, the
registrant's internal control over financial
reporting.

The registrant's principal executive officer and principal financial
officer, however, voluntarily are reporting the following information:

In August of 2006 the registrant's investment adviser
enhanced its internal procedures for reporting performance
information required to be included in prospectuses.
Those enhancements involved additional internal controls
over the appropriateness of performance data
generated for this purpose.  Such enhancements were made
following an internal review which identified
prospectuses relating to certain classes of shares of
a limited number of registrants where, inadvertently,
performance information not reflecting the deduction of
applicable sales charges was included. Those prospectuses
were revised, and the revised prospectuses were distributed to
shareholders.


ITEM 12. EXHIBITS.

File the exhibits listed below as part of this Form. Letter or number the
exhibits in the sequence indicated.

(a) Any code of ethics, or amendment thereto, that is the subject of the
disclosure required by Item 2, to the extent that the registrant intends to
satisfy the Item 2 requirements through filing of an exhibit.



(b) A separate certification for each principal executive officer and principal
financial officer of the registrant as required by Rule 30a-2 under the Act
(17 CFR 270.30a-2).

Filed herewith.





                                   SIGNATURES

                          [See General Instruction F]


Pursuant to the requirements of the Securities Exchange Act of 1934 and the
Investment Company Act of 1940, the registrant has duly caused this report to be
signed on its behalf by the undersigned, thereunto duly authorized.


(Registrant) Pioneer Municipal High Income Advantage Trust


By (Signature and Title)* /s/ John F. Cogan, Jr.
John F. Cogan, Jr, President

Date November 27, 2009


Pursuant to the requirements of the Securities Exchange Act of 1934 and the
Investment Company Act of 1940, this report has been signed below by the
following persons on behalf of the registrant and in the capacities and on the
dates indicated.


By (Signature and Title)* /s/ John F. Cogan, Jr.
John F. Cogan, Jr., President

Date November 27, 2009


By (Signature and Title)* /s/ Mark Bradley
Mark Bradley, Treasurer

Date November 27, 2009

* Print the name and title of each signing officer under his or her signature.