UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13D
Under the Securities Exchange Act of 1934

(Amendment No. 18)

 

Genomic Health, Inc
(Name of Issuer)

 

Common Stock, par value $0.0001 per share
(Title of Class of Securities)

 

  37244C101  
  (CUSIP Number)  

 

Leo Kirby
667 Madison Avenue, 21st Floor
New York, NY  10065
(212) 339-5633
(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

 

  November 9, 2012  
  (Date of Event which Requires Filing of this Statement)  

 

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g), check the following box. ¨

 

Note:   Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent.

 

*The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

 

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (the “Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

 
 

  

SCHEDULE 13D

 

CUSIP No.   37244C101         Page   2   of   11   Pages
     

 

1

NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS

 

Baker Bros. Advisors, LLC

 

13-4093645

 

2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)

(a) ¨

(b)¨

3 SEC USE ONLY
4

SOURCE OF FUNDS (See Instructions)

 

OO

 

5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e) ¨
6

CITIZENSHIP OR PLACE OF ORGANIZATION

 

Delaware

 

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
7

SOLE VOTING POWER

 

12,130,815

 

8

SHARED VOTING POWER

 

0

 

9

SOLE DISPOSITIVE POWER

 

12,130,815

 

10

SHARED DISPOSITIVE POWER

 

0

 

11

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

 

12,130,815

 

12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (See Instructions) ¨
     
13

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

 

39.4% (1)

 

14

TYPE OF REPORTING PERSON (See Instructions)

 

IA

 

 

(1)Based on 30,749,914 shares of common stock outstanding as reported in the Issuer’s Form 10-Q filed with the SEC on November 9, 2012.

 

Page 2 of 11 Pages
 

SCHEDULE 13D

CUSIP No.   37244C101         Page   3   of   11   Pages
     

 

1

NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS

 

Julian C. Baker

 

2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)

(a) ¨

(b)¨

3 SEC USE ONLY
   
4

SOURCE OF FUNDS (See Instructions)

 

OO

 

5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e) ¨
     
6

CITIZENSHIP OR PLACE OF ORGANIZATION

 

United States

 

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
7

SOLE VOTING POWER

 

12,354,212 (1)

 

8

SHARED VOTING POWER

 

0

 

9

SOLE DISPOSITIVE POWER

 

12,354,212 (1)

 

10

SHARED DISPOSITIVE POWER

 

0

 

11

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

 

12,354,212 (1)

 

12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (See Instructions) ¨
     
13

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

 

40.1% (2)

 

14

TYPE OF REPORTING PERSON (See Instructions)

 

IN, HC

 

 

(1)Includes 49,500 shares of the Issuer’s common stock underlying 49,500 options directly held and 173,897 shares of the Issuer’s common stock directly held by FBB Associates.
(2)Based on 30,749,914 shares of common stock outstanding as reported in the Issuer’s Form 10-Q filed with the SEC on November 9, 2012.

 

Page 3 of 11 Pages
 

 

(3) SCHEDULE 13D

 

CUSIP No.  37244C101         Page   4   of   11    Pages
     

 

1

NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS

 

Felix J. Baker

 

2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)

(a) £

(b) £

3 SEC USE ONLY
   
4

SOURCE OF FUNDS (See Instructions)

 

OO

 

5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e) £
     
6

CITIZENSHIP OR PLACE OF ORGANIZATION

 

United States

 

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
7

SOLE VOTING POWER

 

12,304,712 (1)

 

8

SHARED VOTING POWER

 

0

 

9

SOLE DISPOSITIVE POWER

 

12,304,712 (1)

 

10

SHARED DISPOSITIVE POWER

 

0

 

11

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

 

12,304,712 (1)

 

12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (See Instructions) £
     
13

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

 

40.0% (2)

 

14

TYPE OF REPORTING PERSON (See Instructions)

 

IN, HC

 

(1)Includes 173,897 shares of the Issuer’s common stock directly held by FBB Associates.
(2)Based on 30,749,914 shares of common stock outstanding as reported in the Issuer’s Form 10-Q filed with the SEC on November 9, 2012.

  

Page 4 of 11 Pages
 

 

SCHEDULE 13D

 

CUSIP No.   37244C101         Page   5   of   11   Pages
     

 

1

NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS

 

FBB Associates

 

13-3843860

 

2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)

(a) ¨

(b)¨

3 SEC USE ONLY
4

SOURCE OF FUNDS (See Instructions)

 

OO

 

5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e) ¨
6

CITIZENSHIP OR PLACE OF ORGANIZATION

 

New York

 

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
7

SOLE VOTING POWER

 

173,897

 

8

SHARED VOTING POWER

 

0

 

9

SOLE DISPOSITIVE POWER

 

173,897

 

10

SHARED DISPOSITIVE POWER

 

0

 

11

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

 

173,897

 

12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (See Instructions) ¨
     
13

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

 

0.6% (1)

 

14

TYPE OF REPORTING PERSON (See Instructions)

 

OO

 

(1) Based on 30,749,914 shares of common stock outstanding as reported in Genomic Health, Inc.’s Form 10-Q filed with the SEC on November 9, 2012.

  

Page 5 of 11 Pages
 

 

Amendment No. 18 to Schedule 13D

 

This Amendment No. 18 to Schedule 13D amends and supplements the previously filed Schedules 13D filed by Baker Bros. Advisors, LLC (the “Adviser”), Julian C. Baker, Felix J. Baker and FBB Associates (“FBB” and together with the Adviser, Julian C. Baker and Felix J. Baker, the “Reporting Persons”). Except as supplemented herein, such statements, as heretofore amended and supplemented, remain in full force and effect.

 

Item 3.     Source and Amount of Funds or Other Consideration.

 

The disclosure regarding purchases in Item 5(c) below is incorporated herein by reference.

 

Item 4. Purpose of Transaction

 

Whether the Reporting Persons or their affiliates purchase any additional securities or dispose of any securities, and the amount and timing of any such transactions, will depend upon the Reporting Persons’ continuing assessments of pertinent factors, including the availability of shares of Common Stock or other securities for purchase at particular price levels, the Issuer’s business and prospects, other business investment opportunities, economic conditions, stock market conditions, money market conditions, the attitudes and actions of the board of directors and management of the Issuer, the availability and nature of opportunities to dispose of shares in the Issuer and other plans and requirements of the particular entities. Depending upon their assessments of these factors from time to time, the Reporting Persons or their affiliates may change their present intentions as stated above, including determining to acquire additional securities of the Issuer, including shares of Common Stock (by means of open market purchases, privately negotiated purchases, exercise of some or all of the Warrants, or otherwise) or to dispose of some or all of the securities of the Issuer, including shares of Common Stock, under their control.

 

Except as set forth herein or in previous amendments to this Schedule 13D, as the case may be, the Reporting Persons and their affiliates do not have any present plans or proposals at this time that relate to or would result in any of the transactions described in subparagraphs (a) through (j) of Item 4 of Schedule 13D.

 

Item 5.           Interest in Securities of the Issuer.

 

(a) and (b) Items 7 through 11 and 13 of each of the cover pages of this Amendment No. 18 are incorporated herein by reference. Set forth below is the aggregate number of shares of common stock of the Issuer directly held by each of Baker Bros. Investments, L.P. (“Baker Bros Investments”), Baker Bros. Investments II, L.P. (“Baker Bros. Investments II”), 667, L.P. (“667”), Baker Brothers Life Sciences, L.P. (“Life Sciences”), 14159, L.P. (“14159”) and Baker/Tisch Investments, L.P. (“Baker/Tisch”, and together with Baker Bros. Investments, Baker Bros. Investments II, 667, Life Sciences and 14159, the “Funds”). The information set forth below is based upon 30,749,914 shares of Common Stock outstanding, as reported on the Issuer’s Form 10-Q filed with the SEC on November 9, 2012. Such percentage figures are calculated in accordance with Rule 13d-3 under the Securities Exchange Act of 1934, as amended.

 

Name  Number of
Shares
   Percent of Class
Outstanding
 
Baker Bros. Investments, L.P.   173,897    0.6%
Baker Bros. Investments II, L.P.   13,238    0.0%
667, L.P.   1,567,695    5.1%
Baker Brothers Life Sciences, L.P.   9,914,595    32.2%
14159, L.P.   266,914    0.9%
Baker/Tisch Investments, L.P.   194,161    0.6%

 

Page 6 of 11 Pages
 

 

On April 13, 2012, the Adviser, the Funds, and the general partners of the Funds entered into an amended and restated management agreement (the “Management Agreement”) which gave the Adviser complete and unlimited discretion and authority with respect to the Funds’ investments and voting power over investments. The general partners of the Funds relinquished all discretion and authority with respect to the Funds’ investments and voting power over investments. In connection with the services provided by the Adviser to the Funds, the Adviser receives a management based fee that does not confer any pecuniary interest.

 

The Adviser, and Felix J. Baker and Julian C. Baker as principals of the Adviser, may be deemed to be beneficial owners of shares of common stock directly held by the Funds, and may be deemed to have the power to vote or direct the vote of and the power to dispose or direct the disposition of such securities. Julian C. Baker and Felix J. Baker are also the sole partners of FBB, a general partnership, and as such may be deemed to be beneficial owners of shares of common stock directly held by FBB and may be deemed to have the power to vote or direct the vote and dispose or direct the disposition of those shares.

 

The Adviser, Felix J. Baker and Julian C. Baker each disclaim beneficial ownership of the securities held by each of the Funds and FBB, and this Amendment No. 18 shall not be deemed an admission that the Reporting Persons are the beneficial owners of such securities for purposes of Section 13(d) or for any other purpose.

 

Julian C. Baker and Felix J. Baker are Directors of the Issuer. Felix J. Baker also serves on the Compensation Committee of the Issuer’s Board of Directors.

 

(c) The following transactions in the Issuer’s Common Stock were effected by the Funds noted below during the past 60 days using working capital of the applicable purchasing Fund. All transactions were effected in the open market directly with a broker-dealer. Except as disclosed herein or in any previous amendments to this Schedule 13D, none of the Reporting Persons or their affiliates has effected any other transactions in securities of the Issuer during the past 60 days.

 

Page 7 of 11 Pages
 

 

Name  Date  Number of Shares   Transaction  Weighted
Average
Price/
Share
   Footnotes 
667, L.P.  11/9/2012   1,316   Purchase   25.8254    1 
Baker Brothers Life Sciences, L.P.  11/9/2012   13,447   Purchase   25.8254    1 
14159, L.P.  11/9/2012   324   Purchase   25.8254    1 
667, L.P.  11/9/2012   2,657   Purchase   26.9061    2 
Baker Brothers Life Sciences, L.P.  11/9/2012   27,125   Purchase   26.9061    2 
14159, L.P.  11/9/2012   651   Purchase   26.9061    2 
667, L.P.  11/9/2012   40,412   Purchase   27.8438    3 
Baker Brothers Life Sciences, L.P.  11/9/2012   412,596   Purchase   27.8438    3 
14159, L.P.  11/9/2012   9,905   Purchase   27.8438    3 
667, L.P.  11/9/2012   323   Purchase   27.1612    4 
Baker Brothers Life Sciences, L.P.  11/9/2012   3,298   Purchase   27.1612    4 
14159, L.P.  11/9/2012   79   Purchase   27.1612    4 
667, L.P.  11/9/2012   96   Purchase   26.6801    5 
Baker Brothers Life Sciences, L.P.  11/9/2012   980   Purchase   26.6801    5 
14159, L.P.  11/9/2012   24   Purchase   26.6801    5 
667, L.P.  11/9/2012   585   Purchase   27.8556    6 
Baker Brothers Life Sciences, L.P.  11/9/2012   5,972   Purchase   27.8556    6 
14159, L.P.  11/9/2012   143   Purchase   27.8556    6 
667, L.P.  11/12/2012   16,724   Purchase   27.9374    7 
Baker Brothers Life Sciences, L.P.  11/12/2012   178,978   Purchase   27.9374    7 
14159, L.P.  11/12/2012   4,298   Purchase   27.9374    7 
667, L.P.  11/13/2012   8,691   Purchase   27.9919    8 
Baker Brothers Life Sciences, L.P.  11/13/2012   92,917   Purchase   27.9919    8 
14159, L.P.  11/13/2012   2,231   Purchase   27.9919    8 
667, L.P.  11/14/2012   8,352   Purchase   27.3165    9 
Baker Brothers Life Sciences, L.P.  11/14/2012   92,592   Purchase   27.3165    9 
14159, L.P.  11/14/2012   2,223   Purchase   27.3165    9 

 

(1)This reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $25.42 to $26.34. The Reporting Persons undertake to provide the staff of the Securities and Exchange Commission (the “Staff”), upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

 

(2)This reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $26.42 to $27.25. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

 

(3)This reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $27.65 to $27.99. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

 

(4)This reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $27.13 to $27.20. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

 

(5)This reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $26.66 to $26.73. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

 

(6)This reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $27.66 to $27.96. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

 

(7)This reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $27.61 to $28.33. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

 

Page 8 of 11 Pages
 

 

(8)This reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $27.87 to $28.15. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

 

(9)This reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $26.95 to $27.75. The Reporting Persons undertake to provide the Staff of the Securities and Exchange Commission (the “Staff”), upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

 

(d) Not applicable

 

(e) Not applicable.

 

Item 7. Material to Be Filed as Exhibits.
   
Exhibit 99.1 Agreement regarding the joint filing of this statement.

 

Page 9 of 11 Pages
 

 

SIGNATURE

 

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

 

November 14, 2012

 

  BAKER BROS. ADVISORS, LLC
     
  By: /s/ Scott L. Lessing
    Name: Scott L. Lessing
Title: President
     
    /s/ Julian C. Baker
    Julian C. Baker
     
    /s/ Felix J. Baker
    Felix J. Baker

 

  FBB Associates
     
  By: /s/ Julian C. Baker
    Name: Julian C. Baker
Title: Partner

 

Page 10 of 11 Pages
 

 

EXHIBIT 99.1

 

AGREEMENT

 

In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree that this Statement on Schedule 13D relating to the Common Stock, $0.0001 par value, of Genomic Health, Inc. is being filed with the Securities and Exchange Commission on behalf of each of them.

November 14, 2012

 

  BAKER BROS. ADVISORS, LLC
     
  By: /s/ Scott L. Lessing
    Name: Scott L. Lessing
Title: President
     
    /s/ Julian C. Baker
    Julian C. Baker
     
    /s/ Felix J. Baker
    Felix J. Baker

 

  FBB Associates
     
  By: /s/ Julian C. Baker
    Name: Julian C. Baker
Title: Partner

 

Page 11 of 11 Pages