UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549


FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934.

Date of Report: February 04, 2005
(Date of earliest event reported)

Ventana Medical Systems, Inc.
(Exact name of registrant as specified in its charter) Delaware
(State or other jurisdiction of incorporation)   000-20931
(Commission File Number)   94-2976937
(IRS Employer Indentification Number)   1910 Innovation Park Drive, Tucson, AZ
(Address of principal executive offices) 85737
(Zip Code)  
Registrant's telephone number, including area code: (520) 887-2155


Item 9.01. Financial Statements and Exhibits
(c) Exhibits

Ventana reports fourth quarter and full-year 2004 financial results and a two-for-one stock split.

99.1       Press Release of Ventana Medical Systems, Inc. dated February 04, 2005


SIGNATURE

      Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Dated: February 04, 2005
VENTANA MEDICAL SYSTEMS, INC.

By:  /s/ Nicholas Malden                    
     Nicholas Malden
     Senior Vice President, Chief Financial Officer and Secretary